Are they saying that a "Mediterranean Diet" is associated with increased risk of CHD?
Seems a bit unclear from the last sentence in the "results" section...
Are they saying that a "Mediterranean Diet" is associated with increased risk of CHD?This seems to be a new one on sat fats etc. Not directly statin connected, but cholesterol related
A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
https://www.ncbi.nlm.nih.gov/pubmed/19364995
Yes, very poor that they didn't spell out the direction of the association in each case.Are they saying that a "Mediterranean Diet" is associated with increased risk of CHD?
Seems a bit unclear from the last sentence in the "results" section...
Here is the published report in JAMAAre they saying that a "Mediterranean Diet" is associated with increased risk of CHD?
Seems a bit unclear from the last sentence in the "results" section...
ThanksHere is the published report in JAMA
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1108492
<<<<snip>>>>>>
and increased Mediterranean (0.63 [0.53-0.72]) and high-quality diet patterns (0.63 [0.45-0.81]) were each associated with a significantly lower risk of CHD. Conversely, an increased consumption of trans–fatty acids (RR, 1.32 [95% CI, 1.16-1.48]) and foods with a high glycemic index (1.32 [1.10-1.54]) were associated with a significantly higher risk of CHD (Table 2).<<<<<< endsnip<<<<<
https://twitter.com/holmanm/status/1223291710597476352I bet we won't be seeing that one published in the mainstream press.
I wonder if natural statins would be any safer?Statins could worsen the conditions they are alleged to cure...
http://www.sefofcouncil.net/wp-content/uploads/2015/08/news150825_2.pdf
I can't remember enough about statistical significance to be sure about the figures but the conclusion says:Oops! Atorvastatin increases arterial calcification.. ! Yes you read that right..
https://pubmed.ncbi.nlm.nih.gov/164...ring-treatment-a-randomised-controlled-trial/
View attachment 38274
I can't remember enough about statistical significance to be sure about the figures but the conclusion says:
Conclusion: In contrast to previous observational studies, this randomised controlled trial has shown that, despite reducing systemic inflammation and halving serum low density lipoprotein cholesterol concentrations, statin treatment does not have a major effect on the rate of progression of coronary artery calcification.
It appears statins don't make any difference to calcification, to say it makes it worse is a bit of a stretch.
I wonder if natural statins would be any safer?
https://observer.com/2016/11/doctors-orders-eat-these-8-foods-to-naturally-lower-cholesterol/
Although it is an RCT, The test method does not give any indication of how long the groups were exposed to the test conditions. Since the aetiology of calcification is generally a long term process, then duration will be a prime requirement to be controlled and will have significant effect on the outcome. All the participants were chosen because they already had calcification, so again this distorts the analysis.I can't remember enough about statistical significance to be sure about the figures but the conclusion says:
Conclusion: In contrast to previous observational studies, this randomised controlled trial has shown that, despite reducing systemic inflammation and halving serum low density lipoprotein cholesterol concentrations, statin treatment does not have a major effect on the rate of progression of coronary artery calcification.
It appears statins don't make any difference to calcification, to say it makes it worse is a bit of a stretch.
No. I merely question if the same RCT had been performed using a natural statin or stanol whether it would agree with the Pfizer RCT. Or is there something in the processing into a pill that removes or changes the active ingredients.You are assuming that "lowering cholesterol" is beneficial..
So would they benefit by using natures own statins instead?
Rightly or wrongly that is the opinion of many in the belief that the scientists are telling the truth.Only if you believe that "lowering cholesterol" is a benefit surely..
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