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Message: <blockquote data-quote="Bill_St" data-source="post: 2215394" data-attributes="member: 310899">Undoubtedly there is little direct information on COVID. The very wide differences in numbers released just yesterday does highlight this, although the ratios do not differ as much as the published rates.But the first reference given above tells us for CoV-MERS that :"The largest risk factor for increased disease severity and death is diabetes."The second reference gives us :"One study found that 15/17 (88%) individuals who had diabetes had a poor disease outcome characterized by intensive care unit admission or death compared with 7/18 (39%) individuals who had any type of nondiabetic comorbidity, which suggests that diabetes in particular is a major contributor to MERS-CoV disease severity"In <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094725/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094725/</a> Table 6 gives detail:" univariate analysis (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094725/table/pone.0165978.t006/" target="_blank">Table 6</a>). Diabetes was the co-morbid condition most strongly associated with adverse outcome (p = 0.0002)."It should be emphasised that most of these studies are naturally with respect to the earlier forms of Coronavirus - we need an early update with particular reference to COVID.Those existing studies quoted above should not be ignored in further research</blockquote>

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