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<blockquote data-quote="Winnie53" data-source="post: 2245599" data-attributes="member: 160246"><p>Important...</p><p></p><p><strong>The Marik's COVID-19 Protocol was updated on April 3rd...</strong></p><p></p><p><a href="https://isom.ca/wp-content/uploads/2020/04/EVMS_Critical_Care_COVID-19_Protocol-04.06.2020.pdf" target="_blank">https://isom.ca/wp-content/uploads/2020/04/EVMS_Critical_Care_COVID-19_Protocol-04.06.2020.pdf</a></p><p></p><p>It's written for physicians (and now includes graphics), but here's an excerpt relevant to those of us here...</p><p></p><p>Prophylaxis </p><p></p><p>While there is very limited data (and none specific for COVID-19), the following “cocktail” may have a role in the prevention/mitigation of COVID-19 disease, especially amongst the most vulnerable citizens in our community; i.e. those over the age of 60 years and those with medical comorbidities. While there is no high level evidence that this cocktail is effective; it is cheap, safe and should be readily available. So what is there to lose?</p><p> • Vitamin C 500 mg BID and Quercetin 250-500 mg BID</p><p> • Zinc 75-100 mg/day (acetate, gluconate or picolinate). Zinc lozenges are preferred. After 1-2 months, reduce the dose to 30-50 mg/day.</p><p> • Melatonin (slow release): Begin with 0.3mg and increase as tolerated to 1-2 mg at night</p><p> • Vitamin D3 1000-4000 u/day (optimal dose unknown). Likely that those with baseline low 25- OH vitamin D levels and those > living at 40 degree latitude will benefit the most. </p><p></p><p>Mildly Symptomatic patients (on floor):</p><p></p><p> • Vitamin C 500mg BID and Quercetin 250-500 mg BID (if available)</p><p> • Zinc 75-100 mg/day</p><p> • Melatonin 6-12 mg at night (the optimal dose is unknown)</p><p> • Vitamin D3 1000-4000 u/day</p><p> • Enoxaparin 40-60mg day (if not contraindicated; dose adjust with CrCl < 30ml/min)</p><p> • Optional (and if available): Chloroquine 500 mg PO BID for 5 days or hydroxychloroquine 400mg BID day 1 followed by 200mg BID for 4 days</p><p> • Observe closely</p><p> • N/C 2L /min if required (max 4 L/min; consider early t/f to ICU for escalation of care).</p><p> • Avoid Nebulization and Respiratory treatments. Use “Spinhaler” or MDI and spacer if required.</p><p> • Avoid non-invasive ventilation</p><p> • T/f EARLY to the ICU for increasing respiratory signs/symptoms</p><p></p><p>-----</p><p></p><p>[USER=493719]@jjraak[/USER] [USER=48386]@Indy51[/USER] <strong>And here's one more protocol that I learned about tonight. This will be of interest to those of you who are at "high risk"...</strong></p><p></p><p>Dr. Vladimir Zelenko is a primary care doctor in the US. He practices in area one square mile in size with a population of 35,000. He himself is a cancer patient. He wanted to get ahead of the coronovirus so looked at the protocols used in S. Korea and France. With that information, he has treated 911 patients with a positive test result for COVID-19 or symptoms - (fever. cough, diarrhea, loss of taste or smell, etc.). He has one treatment approach for high risk patients, another for low risk patients. Outcomes to date: 0 deaths, 3 patients intubated - (2 still on, 1 off respirator), 6 patients admitted w/bacterial pneumonia for IV antibiotics - (2 now at home). He's using hydoxycholroquine, azithromycin, and zinc sulfate, all oral medications. Protocol is listed in video. Treatment goal is to <em>avoid</em> hospitalization. My kind of doctor...</p><p></p><p>[MEDIA=youtube]Z7SDemHGl8U[/MEDIA]</p></blockquote><p></p>
[QUOTE="Winnie53, post: 2245599, member: 160246"] Important... [B]The Marik's COVID-19 Protocol was updated on April 3rd...[/B] [URL]https://isom.ca/wp-content/uploads/2020/04/EVMS_Critical_Care_COVID-19_Protocol-04.06.2020.pdf[/URL] It's written for physicians (and now includes graphics), but here's an excerpt relevant to those of us here... Prophylaxis While there is very limited data (and none specific for COVID-19), the following “cocktail” may have a role in the prevention/mitigation of COVID-19 disease, especially amongst the most vulnerable citizens in our community; i.e. those over the age of 60 years and those with medical comorbidities. While there is no high level evidence that this cocktail is effective; it is cheap, safe and should be readily available. So what is there to lose? • Vitamin C 500 mg BID and Quercetin 250-500 mg BID • Zinc 75-100 mg/day (acetate, gluconate or picolinate). Zinc lozenges are preferred. After 1-2 months, reduce the dose to 30-50 mg/day. • Melatonin (slow release): Begin with 0.3mg and increase as tolerated to 1-2 mg at night • Vitamin D3 1000-4000 u/day (optimal dose unknown). Likely that those with baseline low 25- OH vitamin D levels and those > living at 40 degree latitude will benefit the most. Mildly Symptomatic patients (on floor): • Vitamin C 500mg BID and Quercetin 250-500 mg BID (if available) • Zinc 75-100 mg/day • Melatonin 6-12 mg at night (the optimal dose is unknown) • Vitamin D3 1000-4000 u/day • Enoxaparin 40-60mg day (if not contraindicated; dose adjust with CrCl < 30ml/min) • Optional (and if available): Chloroquine 500 mg PO BID for 5 days or hydroxychloroquine 400mg BID day 1 followed by 200mg BID for 4 days • Observe closely • N/C 2L /min if required (max 4 L/min; consider early t/f to ICU for escalation of care). • Avoid Nebulization and Respiratory treatments. Use “Spinhaler” or MDI and spacer if required. • Avoid non-invasive ventilation • T/f EARLY to the ICU for increasing respiratory signs/symptoms ----- [USER=493719]@jjraak[/USER] [USER=48386]@Indy51[/USER] [B]And here's one more protocol that I learned about tonight. This will be of interest to those of you who are at "high risk"...[/B] Dr. Vladimir Zelenko is a primary care doctor in the US. He practices in area one square mile in size with a population of 35,000. He himself is a cancer patient. He wanted to get ahead of the coronovirus so looked at the protocols used in S. Korea and France. With that information, he has treated 911 patients with a positive test result for COVID-19 or symptoms - (fever. cough, diarrhea, loss of taste or smell, etc.). He has one treatment approach for high risk patients, another for low risk patients. Outcomes to date: 0 deaths, 3 patients intubated - (2 still on, 1 off respirator), 6 patients admitted w/bacterial pneumonia for IV antibiotics - (2 now at home). He's using hydoxycholroquine, azithromycin, and zinc sulfate, all oral medications. Protocol is listed in video. Treatment goal is to [I]avoid[/I] hospitalization. My kind of doctor... [MEDIA=youtube]Z7SDemHGl8U[/MEDIA] [/QUOTE]
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