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<blockquote data-quote="Oldvatr" data-source="post: 2336933" data-attributes="member: 196898"><p>It needs -70C apparently, but it is able to be stored in a normal refrigerator for up to 5 days once defrosted. Apparently, the RNA is a single strand (like unzipped DNA) so that makes it fragile. It also needs to have a U particle inserted into it to make it attractive to the immune system. The strand needs to be wrapped in a lipid bubble to allow it to be delivered to the cell where it gets unpacked for use and builds the S-protein without the rest of the DNA bits. This RNA is part of the natural coding system in our bodies and is used extensively as the shorthand shipping manifesto for what it represents. Our cells use this code to recognise useful bits, and the U segment calls in the T-Cells to escort it off the premises, So although this is the first time this technique is being used in humans, it is using natural processes in the body that are fairly well understood in genetic engineering.</p><p></p><p>The two contenders for the prize differ in what they use for the lipid, and this largely explains the different temperatures for long term storage,</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 2336933, member: 196898"] It needs -70C apparently, but it is able to be stored in a normal refrigerator for up to 5 days once defrosted. Apparently, the RNA is a single strand (like unzipped DNA) so that makes it fragile. It also needs to have a U particle inserted into it to make it attractive to the immune system. The strand needs to be wrapped in a lipid bubble to allow it to be delivered to the cell where it gets unpacked for use and builds the S-protein without the rest of the DNA bits. This RNA is part of the natural coding system in our bodies and is used extensively as the shorthand shipping manifesto for what it represents. Our cells use this code to recognise useful bits, and the U segment calls in the T-Cells to escort it off the premises, So although this is the first time this technique is being used in humans, it is using natural processes in the body that are fairly well understood in genetic engineering. The two contenders for the prize differ in what they use for the lipid, and this largely explains the different temperatures for long term storage, [/QUOTE]
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