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CPEP Test

I’m wrong? Wouldn’t that be an opinion? I was being lighthearted yes, flippant? If you so. I’m not sure what that means, is that when you don’t care what someone who assumes they are correct, replies to your post on the internet says? You could be correct (again) please forgive me, I’ll toddle off to my sad and serious box, seems a bit full but I’ll try to squeeze in.
 
Good morning lovely people.

Can we please keep the topic in line with Duncan's query & not tune it in to "bicker's world."

Many thanks in advance..
 
ert said:
Low C-peptide (below the normal range) will result in a rapid deterioration onto insulin, which supports type 1. Sometimes beta cells are killed by a virus.
Click to expand...

My understanding is that a virus does not equate to an autoimmune disease.
You appear to be saying that T1 can have multiple causes.
However further down you yet again define T1 as an autoimmune disease.

To my mind this suggests that there still isn't a clear definition.
 
LittleGreyCat said:
Low CPEP and no antibodies on diagnosis.
Generally diagnosed as T1 but lacking any evidence of autoimmune disease.
Where does that fit into the great scheme of things?
Click to expand...

just my opinion here.
Repeated cpeptide should be done over time if the initial diagnosis is unclear. A LADA/type1 would get progressively results over time. If you’ve quickly ended up on insulin and low carb didn’t work I’d say that too adds weight to the type 1 position and vice versa. Sadly not every case is clearcut in the early years and if you wait too long (10yrs plus of uncontrollable type 2) then it may never be clear why a pancreas has stopped producing insulin. This is why any unclear case should have c peptides, and more than one if necessary.

Antibodies don’t always show up in all type 1 diagnosis and can fade over time once they’ve “destroyed” the relevant cells and finished their job.
 
Wouldn’t a virus fall into type 3? Same as injury, disease and surgery? Ie lack of insulin but not autoimmune.
 
T1 is an autoimmune disease. Sometimes the immune system is triggered by a virus. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539350/
 

Technically a t2 can become T2 as well but they just get call t1 with insulin resistance


Although rare I’m sure a t2 could get an autoimmune issue that can cause t1 as well
 
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