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Creatine and glucose metabolism

Melgar

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This maybe of interested for some if you.

I’ve been taking 5mg of creatine per day for a couple of months now. My Dr suggested I take it as I was experiencing some brain fog due to the statins I’m on. He told me he takes creatine and has found it makes a difference on his own cognition. I am also pleased to say that I have had similar results. My fogginess seems to have lifted . I also had aching leg muscles, I’ve had aching leg for a few years, and prior to going on statins. The leg aches have cleared up too. So I’m very pleased.

Furthermore, I have been controlling my blood sugars with exercise and Bupropion. Bupropion is classed as an antidepressant, but it can be used off label for ADHD. It has been found it promotes insulin secretion. So, along with exercise, this has brought my HbA1c ‘s to the low 6’s. Of note I’m not on a low carb diet.

The interesting thing is this, my blood sugars have now dropped further, I’m now experiencing low blood sugars, I’ve had 5 low blood sugar events this past 7 days. I’ve always had fluctuating blood sugars, and have a history of hypos, but I’ve not had this many low blood sugar events in such a short period of time. The only change I’ve made is the use of creatine.

I did a bit of research, and sure enough, creatine has been speculatively associated with improved glucose metabolism.

“Creatine supplementation has the potential to promote changes in glucose metabolism that may favor a healthier metabolic profile. This may be particularly true when exercise training is provided along with this supplement, as creatine seems to enhance the training adaptations.”

If this is true, and my n=1 is suggestive it might be for me, then that is an unexpected positive. Of course, this is my take, and like any health supplement, it is not neutral, it comes with possible side effects depending on one’s own heath profile and other medications. Creatine was my own Dr’s suggestion, and for me it has proved a positive.
This is remains a very speculative n=1 take on creatine from my experience, but thought I would share.



Edited spelling plus the addition of one extra study.
 
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The possible uptake of glucose from the blood to the muscle is one reason I’m trying creatine….and I want to discourage muscle loss. At 68 I find it very hard to build muscle and keep it! I’m just a little less than a month in so results are pending. I have noticed a lower blood glucose right after and during my morning workouts….but it does rise again later.
I’ve been doing some major stress eating lately and now have that under control….therefore any blood readings have been…well….suspect. All good now, my head is in a good place so the experiment continues.
 
There have been a couple of articles in the New Scientist magazine over the past year about the health benefits of creatine supplements. Positives include better muscle strength and increased brain cognition, especially in “older folks”! The benefits for younger people are not clear.
There have also been some studies that show some protection against Alzheimer’s and others that show a reduction in LDL cholesterol.
Results for glucose control seem to be mixed, so I think that as ever, individual reaction is probably the key.
As an older person myself, I am interested in trying creatine, the dosage in powder form seems to be 5 gms .
 
One day the mysteries of our metabolism and the effects of our hormones will be clearer.
It is out there somewhere. Not enough research is being done.
 
One day the mysteries of our metabolism and the effects of our hormones will be clearer.
It is out there somewhere. Not enough research is being done.

fair few trials are in progress which hopefully with enough signups and time even unlikely solve the mystery in the near future but perhaps may further assist several generations down the line
 
I may have to try some, how are you taking it? as a tablet or in a drink?
@lessci I take the pure powder form no added flavours- Creatine Monohydrate - so it’s water soluble. I take 5 mg per day. I stir mine into a small amount of milk.
 
Yes, @Bcgirl I agree, it could be the depleting muscle mass that adds to glucose problems, so as creatine helps build muscle mass, along with exercise , the results may be a greater uptake in blood sugars.
 
@Rustytypin, yes as always, it’s individual. I do a lot of exercise and the results seem to favour creatine along with exercise. I take 5 mg daily which is what my Dr advised.
 
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