Dapagliflozin

[84green]

Hi

I haven't posted here for some time but this forum was a great help to me when I was first diagnosed with T2. My BG is currently well controlled (which I put down to significant weight loss a few years ago). My BP less well controlled. I currently take metformin (500g), rosuvastatin, ramipril, and aspirin - all of which I seem to tolerate, although I needed to switch to a slow release metformin.

I recently had a urinalysis which showed my ACR elevated to 7.9mg/mol. Not huge, but the first time it has been abnormal. My renal blood tests are normal and my eGFR has always been above 90. I appreciate that this is a one off and further tests will confirm microalbuminuria (or not). As a result, I mentioned dapagliflozin to my GP as I understand it helps kidney function and is effective in reducing ACR.

My practice isn't concerned about the ACR at this stage but is happy to swap the metformin for dapagliflozin if I wanted. I have read the benefits and side effects of dapagliflozin. I am inclined to try it, mainly as a protection for my kidneys, but wanted to ask here if anyone has any direct experience of this medication.

Thanks.

 

[Outlier]

I was put on it while in hospital, with no information or explanation. When I came home after 5months, I checked it out and discovered I was supposed to eat carbs with it, though no safe minimum was given - I'd been keto for 7 years. At first I ignored the advice, as no harm seemed to be happening, then I asked my GP who seemed unconcerned - there's a risk of ketoacidosis - then spoke with DN who was very concerned and asked me to up my carbs. I've since increased these by a small amount. I've had no adverse reactions from the Dapa, and seem to be tolerating it very well. As it's diuretic as well, its effects are inconvenient, but I time taking it with the days' schedules.