Do larger than ususal doses effect release of insulin?

[SB2013Pump]

I have suddenly had unexplained highs all evening and now mild ketones.
I started at 6.8 before my evening meal.
My meal was a lot larger than usual so I injected a mich higher dose that I usually do (10 units)
I am very sensitive to insulin so my BI is only 15 units a day

Since the meal I have been sky high (18+) and now developing mild ketones,
so I am on the 2 hour regime of checking and correcting

So far I have:
- checked that I had injectied (I have an insulcheck on my pen)
- changed all my insulins over (even though according to the labels I put on them they are not more than 28 days out of the fridge)
- checked that there is not a lump where I injected which might have impeded the take up of insulin
Any other ideas?

I do not feel ill apart from feeling rough from being high
My control is usually very good and I am running out of ideas and seem to be rising rather than falling

Is there any way that taking a larger dose of insulin than usual could limit the uptake of the insulin?
Any other ideas?

 

[elainechi]

lm sure someone will give you a posible reason......but sometimes a fatty carby meal can take ages for yhe insulin to work and thus you get high bs then later they shoot down...not sure why!!!

 

[Glen]

Larger does will be absorbed slightly slower unit for unit than smaller doses. However my guess would be you are coming down with a cold or flu.

 

[angieG]

Did your levels return to normal, or are you still high this morning?

What did you eat?

Hope you okay
Angie

 

[noblehead]

As a suggestion for future reference try splitting the dose and injecting in different sites, I'm not going to say it will work but may be worth a try.

It may well be that the insulin didn't absorb properly or you miss calculated the carb content of your food, it can also be the case that your starting with a cold or flu and have yet to get the symptoms, either way I hope all is well today

 

[SB2013Pump]

Thanks for all the helpful ideas

I was back to normal (6.5) this morning after two correction doses in the night.
But its lunchtime I am high again, even thought I had my normal breakfast and normal dose, so I know that there is no problem with Carb counting or anything else. Some sniffles so perhaps it is an iminent cold. Aren't we lucky to get the early warngin signs. I shall monitor and up the basal if high again this evening.

With recent retirement every day is now different so it is difficult to isolate the changes that happen.
I am usually on target or no more than about 8 morning and lunchtime, not so good at bedtime as the evening meals are abit more fatty on occassions, and if we eat late there is active insulin when I go to bed. I know that it would all be solved if I just ate the same every day and had no fat, but this is life.

However I know that I am not a robot so I shall just have to keep working on it. We have recently tried some of the ideas from think Like pancreas fro reducing after meal highs. So now I inject a guess bolus about 20 min before meal (assuming that I am not below target) and we walk for 30 minutes after the meal. I just have to know when we eat whether the walk will win or we give in to a bit of a lazier approach (but then Lewis and Borgen have finished now so less excuses now.

Thanks again

Sue

 

[SB2013Pump]

Hello all

The levels were up and down again yesterday and now finally the cold has arrived, as suggested by a couple of you.
So I have upped the basal rate a bit and all is level again. Also just got my lowest HbA1c back fro ages so feeling a lot better even if a bit bunged up.

Thanks for all the ideas and I shall definietly consider splitting bolus, especially as once on a pump I can programme it to do that for me. I foudn with MDI I planned to do that and then forgot so abandoned the attempts. hopefully on a pump it will prove to be more reliable, or at least I will

Sue