I am very interested in the theory of insulin resistance and how you know whether you are not producing enough or whether your body just rejects it. I wonder - without continual insulin testing how anyone knows?
Because Prof T does not spend too long talking about IR more about a lack of insulin producing cells. And that does bother me about the research.
When you say bounce back
@ickihun do you mean the times you may have put weight back on?
I do not see this as a fix - more maintenance on a very very long journey of lifestyle changes.
I unfortuntely know how much insulin I'm injecting and that I'm producing my own insulin too.
How do I know?
Because before and in early stages of insulin injection therapy I missed injections which was accidental but my bgs eventually changed to hypos on not eating thereafter, thinking I was compensating for high bg (due to missed inj). Type1s don't get that. They never hypo unless they have taken too much insulin injected units. A type 1 will increase their bg levels without insulin. (Unless their in the honeymoon period of their disease developing).
So.
The insulin I'm injecting is at
least the measure of my insulin plus
more.
On that theory I'm highly insulin resistant as I'm injecting 66units of stronger basal insulin and 60units of novarapid (bolus) and metformin, max dose.
Now.... some will be due to weight of body as insulin is always been needed per lb/kg.
So.... weight loss will reduce my insulin need.
However, that is just part of the solution.
The liver, muscles and other organ uptake of glucogen which converts to glucose on release is overwrked or overactive for me.
Metformin curbs that, a little. My insulin need is also for counteracting glucose dumping.
If I fast for a week but drink plenty of water I'm hyper, not hypo
without insulin injections. So my pathway for my own insulin to work correctly is blocked. Due to obesity or fatty liver? Probables both.
Type 2 insulin resistance is a problem with the liver etc not pancreas, like type 1s.
That is why weight loss helps hugely in obese type 2s. But thin type2s have an overactive liver etc. mainly.
Just remember we are not born obese so therefore additional influences cause obesity.