Most definitely yes. Feel rough as anything if I have more than 2 glasses of wine. TBH I used to drink far too much even after diagnosis but in last 2 years have cut out alcohol almost completely. The only time I drink a bit is at weddings, special occasions (and only if they've got a nice cava or a glass of bubbly) and on holidays but I'm ultra careful and watch those BSs like a hawk - which is a pain and another reason why I don't bother to do it regularly any more. Diet coke and soda water with a slice of lime girl now. Getting older too and seeing the folly of my ways when I drank too much.