Not if they can figure out the exact process to make best use of them. If a stem cell is given the individual patient’s genetic information, that cell should be able to function as a beta cell and produce insulin in a natural way. There would be no rejection problem because the immune system would recognize that beta cell as your own, not an invader.stem cells? Wouldn't our immune system kill them too, even if we could grow another pancreas?
I think she meant that having T1 means our immune system already killed off our very own beta cells, so why wouldn't it do the same thing with the new beta cells?There would be no rejection problem because the immune system would recognize that beta cell as your own, not an invader.
Do I understand correctly that once provoked autoimmune aggression will not last a lifetime?Nobody knows for sure what the autoimmune response would be to a fresh set of customized beta cells but the thinking is that the killing of beta cells requires a trigger, like a virus, and they may be able to deal with that.
I hear this very often from diabetics themselves, but I have never seen a serious scientific work on this topic (if you have a link, please share it). When I have to show my passport or tell people how old I am, they are usually very surprised that I am so old, and recently I was told that I look like a schoolgirl, although I graduated from school 10 years ago. Is that the case with you too?
I thought that the lack of insulin slows down aging... I don't know where this thought came from, but I remember that it was often repeated by diabetics themselves, and I notice for myself that I don't look my ageHi,
Oddly, I’ve noticed (or tripped over.) online the occasional fixation regarding exogenous insulin (commonly associated with T1.) from the misguided that are not even in a diabetic range A1c wise? (There is basically no DX regarding the person enquiring.)
I wonder if people who want to take insulin without having diabetes know that this medicine can lead to death? I'm scared for them, because, unlike us, no one taught them to cope with itSo why would someone wish to obtain insulin when not needed? (Or any other diabetic related drug in that case. Insulin isn’t the only one.)
“Freudian slips” sometimes suggest this topic title as the “reasoning.” A misconception derived from somewhere it has “advantages” on slowing down the ageing process.
I thought that the lack of insulin slows down aging... I don't know where this thought came from, but I remember that it was often repeated by diabetics themselves, and I notice for myself that I don't look my age
I wonder if people who want to take insulin without having diabetes know that this medicine can lead to death? I'm scared for them, because, unlike us, no one taught them to cope with it
especially for such people: you will die if you do this!I’m being very careful how to discuss this on an open forum. By the same token others under misguidance can & do equate rapid unhealthy weight loss due to insulin omitting or even pre DX with a failing pancreas, sadly to slowing the ageing process.
No, the evidence is that as things stand with Type1, it will. But a successful cure using stem cells would sidestep this problem, preventing an autoimmune response that kills the new beta cells.Do I understand correctly that once provoked autoimmune aggression will not last a lifetime?
Sorry I'm being so dumb, but what in this case will prevent the immune system from attacking new beta cells?No, the evidence is that as things stand with Type1, it will. But a successful cure using stem cells would sidestep this problem, preventing an autoimmune response that kills the new beta cells.
Two things.Sorry I'm being so dumb, but what in this case will prevent the immune system from attacking new beta cells?
Hope this was a little clearer.
If they understand this, with an early diagnosis of diabetes, we will be able to cure a person without insulin and operations, won't we? Although T1 is usually diagnosed too late when we are already in a precomatous state (because who will worry that the child just often wants to drink)They’ll have to figure out what triggers the immune system to begin the attack against the beta cells we’re born with. There might be different triggers, like different viruses or other things in the environment. Once they understand how these triggers work, they can create a way to prevent them from restarting the autoimmune attack and destroying our new beta cells.
Yes, it's clearer now. Thank you very much!
If they understand this, with an early diagnosis of diabetes, we will be able to cure a person without insulin and operations, won't we? Although T1 is usually diagnosed too late when we are already in a precomatous state (because who will worry that the child just often wants to drink)I wonder how much time passes between the onset of autoimmune aggression and the diagnosis of the disease
perhaps you are referring to this research (I don't know if it is possible to post a link on the forum) https://www.intechopen.com/chapters/24183I know about ten years ago they were doing a study on T1 relatives who had various gene markers (and might therefore be more susceptible to becoming T1) to see if various treatments would stop them from developing it. My daughter tried enrolling, but she didn't have the right markers to take part so I don't know what the end result was. But there are/were studies on the prevention aspect.
do I understand correctly that you inherited diabetes, but your diabetes did not affect your children at all? has pregnancy had a big impact on your health? If I ask something unacceptable, just don't answer.
perhaps you are referring to this research (I don't know if it is possible to post a link on the forum) https://www.intechopen.com/chapters/24183
I'll try to attach a pdfI don't think that link works.
I've always been told that if I want to give birth, it's better to do it before 25 and only once. Although I decided for myself that I would not have children. It always seemed to me that if I got pregnant, it was almost the same as death. I have often heard that women went blind after pregnancy or became disabled for another reason, and children were born and immediately fell into a hypoglycemic coma.
I can't make up my mind to have a cat, let alone a childThere are plenty of successful pregnancy stories on the pregnancy subforum here.
You could always start with a cat and go from there.I can't make up my mind to have a cat, let alone a childBut I can't help but admit the fact that I am inspired by how well everything is with you
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