Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Insulin Pump Forum
does this mean I have not been getting Basal?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="irrationalJohn" data-source="post: 1009077" data-attributes="member: 187593"><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">I hadn't heard of Tresiba before now so I am not familiar with it. After Googling around a bit, it looks like a much longer basal insulin source. After using it for 8 days or longer it appears to remain active for up to 42 hours (a day plus 18 hours).</span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">I grabbed the graph at the end of this post from <a href="http://www.novo-pi.com/tresiba.pdf" target="_blank">this PDF of the "highlights of prescribing information" leaflet</a> I found online. To my untrained eye it seems "flatish" rather than flat. There is peaking between 6 to 12 hours after injection and then trailing off slowly after that. So ... probably not too much different than Lantus or Levemir other than the dosage specifics and lasting longer?? Perhaps?</span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">I apologize for still not understanding the situation, but I am still not clear one whether that previous "busy" graph is a reasonable approximation of the basal settings Gaz-M is currently using or not. But I wanted to attempt to make it clear why I don't think <strong>anyone</strong> should ever use basal settings similar to what that graph seems to imply.</span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">My main concern with "busy" basal settings is that, in my opinion, it obscures what your <strong><em>actual (effective) </em></strong>pump basal settings might be. You simply can <strong>not</strong> turn around the dynamics of subcutaneous insulin infusion in 15 minutes or even a 1/2 hour. Programming settings into a pump which jerk like that simply do not give an accurate impression of what the glucose lowering effect of the pump's basal actually is. So what's the point?</span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">The actual glucose lowering effect is going to work out to be some mushed out average of the programmed rates. For example, a rate of 0.525 U for an hour followed an hour of 0.475 U is most likely indistinguishable from two hours of 0.500 U, no? And what would setting 0.350 U for 45 minutes followed by 15 minutes at 0.300 accomplish versus an hour at 0.325? So why do it? </span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">It seems to be adding pointless complexity to a matter which is already hard enough to sort out. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite12" alt="o_O" title="Er... what? o_O" loading="lazy" data-shortname="o_O" /></span></p><p><span style="font-family: 'Verdana'"></span></p><p><span style="font-family: 'Verdana'">As mentioned earlier, the more common (?) practice appears to be to start people off with a single basal rate. This may be partly an effort to mimic the single basal insulin of the previous MDI treatment. But I also believe this approach is taken to reduce complexity and make it easier to get a better idea of what your body's basal insulin needs actually are. When the pump basal settings jump around like that you just don't really know what your basal settings are. So how can you then "fix" them? <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite9" alt=":eek:" title="Eek! :eek:" loading="lazy" data-shortname=":eek:" /></span></p><p></p><p>Anyway, I look forward to hearing about what happens on Tuesday (tomorrow).</p><p></p><p><img src="http://i.imgur.com/4uicgGwl.png" alt="" class="fr-fic fr-dii fr-draggable " style="" /></p></blockquote><p></p>
[QUOTE="irrationalJohn, post: 1009077, member: 187593"] [FONT=Verdana] I hadn't heard of Tresiba before now so I am not familiar with it. After Googling around a bit, it looks like a much longer basal insulin source. After using it for 8 days or longer it appears to remain active for up to 42 hours (a day plus 18 hours). I grabbed the graph at the end of this post from [URL='http://www.novo-pi.com/tresiba.pdf']this PDF of the "highlights of prescribing information" leaflet[/URL] I found online. To my untrained eye it seems "flatish" rather than flat. There is peaking between 6 to 12 hours after injection and then trailing off slowly after that. So ... probably not too much different than Lantus or Levemir other than the dosage specifics and lasting longer?? Perhaps? I apologize for still not understanding the situation, but I am still not clear one whether that previous "busy" graph is a reasonable approximation of the basal settings Gaz-M is currently using or not. But I wanted to attempt to make it clear why I don't think [B]anyone[/B] should ever use basal settings similar to what that graph seems to imply. My main concern with "busy" basal settings is that, in my opinion, it obscures what your [B][I]actual (effective) [/I][/B]pump basal settings might be. You simply can [B]not[/B] turn around the dynamics of subcutaneous insulin infusion in 15 minutes or even a 1/2 hour. Programming settings into a pump which jerk like that simply do not give an accurate impression of what the glucose lowering effect of the pump's basal actually is. So what's the point? The actual glucose lowering effect is going to work out to be some mushed out average of the programmed rates. For example, a rate of 0.525 U for an hour followed an hour of 0.475 U is most likely indistinguishable from two hours of 0.500 U, no? And what would setting 0.350 U for 45 minutes followed by 15 minutes at 0.300 accomplish versus an hour at 0.325? So why do it? It seems to be adding pointless complexity to a matter which is already hard enough to sort out. o_O As mentioned earlier, the more common (?) practice appears to be to start people off with a single basal rate. This may be partly an effort to mimic the single basal insulin of the previous MDI treatment. But I also believe this approach is taken to reduce complexity and make it easier to get a better idea of what your body's basal insulin needs actually are. When the pump basal settings jump around like that you just don't really know what your basal settings are. So how can you then "fix" them? :eek:[/FONT] Anyway, I look forward to hearing about what happens on Tuesday (tomorrow). [IMG]http://i.imgur.com/4uicgGwl.png[/IMG] [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Insulin Pump Forum
does this mean I have not been getting Basal?
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…