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Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
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<blockquote data-quote="MikeFailBetter" data-source="post: 1907149" data-attributes="member: 493399"><p>I have been doing monthly FMD since August, 2017, starting with 3 days, then 4, and now 5 days for the last three months. </p><p></p><p>This month, for the first time since I started the FMD, I feel I have improved blood sugar control. I have cut my Lantus from 6 to 3 (while keeping FBG around 84mg/dL), and decreased the frequency of my small boluses (1-2 units humalog as needed). I can only hope this is for real.</p><p></p><p>I don't think I was refeeding properly until this month's FMD. Before, I would use extra insulin to keep my sugars as controlled as possible and I would limit my carbs more than usual since the IR seemed higher; my diet would be high in fat.</p><p></p><p>After reading the information on refeeding in this forum and in Longo's book, I decided on higher carbs and a little less blood sugar control for this refeeding. For the 3 refeeding days, I went from HCLF to LCHF while ramping up my calories toward my usual 3200 (BMI 22, active lifestyle). I purposely allowed sugars in the 150mg/dL range for periods of hours, while keeping overnight sugars well-controlled. I exercised much more than usual to control my sugars without using as much insulin and to promote IGF-1. Before my morning injections, I also took 20min sauna-like showers to get my BPM to 130 in order to increase IGF-1.</p><p></p><p>Here is the profile of my refeeding days:</p><p></p><ul> <li data-xf-list-type="ul">day 1: 2072kcal; P/C/F: 120g/190/64, or 23%/49%/28% of calories<br /> </li> <li data-xf-list-type="ul">day 2: 2447kcal; P/C/F: 148g/156/116, or 25%/34%/42%</li> <li data-xf-list-type="ul">day 3: 3243kcal; P/C/F: 132g/142/221, or 16%/24%/60%</li> </ul><p>After refeeding I returned to my usual LCHF diet, with around 65g carb per day.</p></blockquote><p></p>
[QUOTE="MikeFailBetter, post: 1907149, member: 493399"] I have been doing monthly FMD since August, 2017, starting with 3 days, then 4, and now 5 days for the last three months. This month, for the first time since I started the FMD, I feel I have improved blood sugar control. I have cut my Lantus from 6 to 3 (while keeping FBG around 84mg/dL), and decreased the frequency of my small boluses (1-2 units humalog as needed). I can only hope this is for real. I don't think I was refeeding properly until this month's FMD. Before, I would use extra insulin to keep my sugars as controlled as possible and I would limit my carbs more than usual since the IR seemed higher; my diet would be high in fat. After reading the information on refeeding in this forum and in Longo's book, I decided on higher carbs and a little less blood sugar control for this refeeding. For the 3 refeeding days, I went from HCLF to LCHF while ramping up my calories toward my usual 3200 (BMI 22, active lifestyle). I purposely allowed sugars in the 150mg/dL range for periods of hours, while keeping overnight sugars well-controlled. I exercised much more than usual to control my sugars without using as much insulin and to promote IGF-1. Before my morning injections, I also took 20min sauna-like showers to get my BPM to 130 in order to increase IGF-1. Here is the profile of my refeeding days: [LIST] [*]day 1: 2072kcal; P/C/F: 120g/190/64, or 23%/49%/28% of calories [*]day 2: 2447kcal; P/C/F: 148g/156/116, or 25%/34%/42% [*]day 3: 3243kcal; P/C/F: 132g/142/221, or 16%/24%/60% [/LIST] After refeeding I returned to my usual LCHF diet, with around 65g carb per day. [/QUOTE]
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