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Fats and Insulin Resistance
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<blockquote data-quote="Sean_Raymond" data-source="post: 2354656" data-attributes="member: 403497"><p>Hi. I've utilised carbohydrate reduction with calorie reduction as well as maintenance diets which were low carbohydrate and just a low carbohydrate diet with no restrictions.</p><p></p><p>In terms of compliance, I can personally attest to a strict adherence by myself and partner but with patients/friends/colleagues I would have to rely on their testimony as with anyone else. That'll always be a cofounder. </p><p></p><p>How can I be sure it was low enough for that persons insulin resistance? You mean beyond some carbohydrate intolerance threshold? If so, that is a fair point in the sense that in those that low CHO did not work for, was the carb still set too high. I could not say as I did not have the time with those particular people to trial various ratios. </p><p></p><p>The diets were designed to provide around 50g of CHO per day and from what I recall were calculated to 10-15% of energy needs. I kept protein to roughly 20% of energy needs. Such diets should have caused a decent drop in insulin (these were not measured) and so not seeing weight loss in those whose diets were matched to their energy needs (I wasn't expecting any - blood sugars were generally better) would need to be explained if the insulin theory (independent of calories) is correct.</p><p></p><p>As I say, you make a fair point regarding needing to trial different carb amounts - which my knowledge and experience is lacking in - but surely you'd agree that insulin reduction per se should create at least some weight loss if it is the major driver of weight/fatness? </p><p></p><p>You ask how this fits in those with insulin resistance yet I have seen T2DM patients lose weight on low calorie diets frequently and studies that looked at whether insulin resistance affect weight loss found it didn't whilst numerous studies show people losing weight - many low CHO V High CHO studies have shown this</p></blockquote><p></p>
[QUOTE="Sean_Raymond, post: 2354656, member: 403497"] Hi. I've utilised carbohydrate reduction with calorie reduction as well as maintenance diets which were low carbohydrate and just a low carbohydrate diet with no restrictions. In terms of compliance, I can personally attest to a strict adherence by myself and partner but with patients/friends/colleagues I would have to rely on their testimony as with anyone else. That'll always be a cofounder. How can I be sure it was low enough for that persons insulin resistance? You mean beyond some carbohydrate intolerance threshold? If so, that is a fair point in the sense that in those that low CHO did not work for, was the carb still set too high. I could not say as I did not have the time with those particular people to trial various ratios. The diets were designed to provide around 50g of CHO per day and from what I recall were calculated to 10-15% of energy needs. I kept protein to roughly 20% of energy needs. Such diets should have caused a decent drop in insulin (these were not measured) and so not seeing weight loss in those whose diets were matched to their energy needs (I wasn't expecting any - blood sugars were generally better) would need to be explained if the insulin theory (independent of calories) is correct. As I say, you make a fair point regarding needing to trial different carb amounts - which my knowledge and experience is lacking in - but surely you'd agree that insulin reduction per se should create at least some weight loss if it is the major driver of weight/fatness? You ask how this fits in those with insulin resistance yet I have seen T2DM patients lose weight on low calorie diets frequently and studies that looked at whether insulin resistance affect weight loss found it didn't whilst numerous studies show people losing weight - many low CHO V High CHO studies have shown this [/QUOTE]
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