Hi Chillout,
Gliclazide is one of a class of drugs known as sulphonylureas. These tablets work by stimulating your pancreas to produce more insulin hormone, which lowers your blood glucose. They are frequently used in combination with Metformin or other tablets to control your diabetes.
What is the dose?
Gliclazide is also known as DiamicronR and is available as 80mg tablets which are scored and can be halved in order to take a 40mg dose. The usual starting dose is 40 –80 mg daily. The maximum daily dose is 320mg. There is also a slow-release version that is available in a 30mg tablet.
When do I need to take them?
If taken as a single dose then Gliclazide should be taken about 20 minutes before breakfast. If taken twice daily, then before breakfast and before your evening meal.
Are there any side effects?
Side effects of sulphonylureas are generally mild and infrequent and sometimes cause nausea or headache. Older drugs in this class were known to cause facial flushing after alcohol, but this does not occur with the newer ones.
Sulphonylureas unfortunately have a tendency to promote weight gain. This can be reduced by diet and exercise. They may occasionally cause hypoglycaemia (low blood sugar level). This is most likely to occur during the late morning if you have been physically active or if lunch is late. Symptoms would be faintness, sweating and disorientation. Eating a snack such as a couple of plain biscuits will quickly make you feel better. Alternatively eat a glucose tablet. It is important to be aware of this side effect when driving.
Hope that helps.
