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Message: <blockquote data-quote="Mep" data-source="post: 1207679" data-attributes="member: 211362"><p>I noticed when I used to be on that drug that was when I wasn't losing any weight despite doing 2 hours of exercise daily (I was doing an average of 16000 steps per day or more, plus weights) and eating right.  I just about went insane.  I then started getting very sick and my exercise routine went out the window.   But my thoughts on it is that Gliclazide actually stimulates the pancreas to produce more insulin.  So effectively you're not only insulin resistant already, but you've got excess insulin floating around in your blood.... of course insulin is a fat storing hormone.   I think that could be the reason for why you're noticing weight gain.  It is probably a good idea to discuss with your doctor and see if there are any other alternatives to helping you keep your sugar levels down.  These days I don't have a choice as I no longer produce much insulin anyhow so meds won't help me.   I wish you the best. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile    :)" loading="lazy" data-shortname=":)" /></p></blockquote><p></p>

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