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How do i find out...

Patch

Patch

Well-Known Member
Messages
2,981
Location
Bristol
Type of diabetes
Treatment type
Insulin
...what the actual reason for being Type 2 is? My understanding of type 2 is that EITHER:

1) My body does not produce ENOUGH insulin, OR
2) My body DOES create enough insulin (maybe even TOO much, resulting in being overweight), but my cells are not able to absorb the insulin/glucose from my blood.

Does anybody know of a test that can be carried out to determine what is actaully happening inside me? Could a C-Peptide test give me the answer???

EDIT: Just had an after thought. Could it be that my body DOES create enough insulin to deal with the food I eat, but that my Liver is producing more glucose then that amount of insulin can handle?
 
Thanks for the reply Ken - but that article doesn't really answer my questions...
 
Hi Patch,

Ken's link contains the answers I would have given.
There are 2 facets of T2:-
1 - Insulin Resistance, whereby the body is unable to make efficient use of the insulin available.
2 - Insulin insufficiency, whereby the pancreas has lost so many insulin producing beta-cells that it works at a very reduced rate and so does not peroduce enough insulin.

GOOD NEWS :-
Insulin Resistance can often be resolved by weight loss, hence if we can overcome insulin resistance and then reduce the amount of insulin required by the reduction of carbohydrate intake, then we can often cope with our reduced insulin production.
This is why the term "Diabetes Reversal" is used as opposed to cured.

Regards Steve.
 
When a patient has newly diagnosed type 1 or type 2 diabetes, C-peptide can be used to help determine how much insulin the patient’s pancreas is still producing.

In type 2 diabetes, there is insulin resistance and a compensatory increase in insulin production and release that can also lead to beta cell damage. Type 2 diabetics usually are treated with oral drugs to stimulate their body to make more insulin and/or to cause their cells to be more sensitive to the insulin that is already being made. Eventually, because of the beta cell damage, type 2 diabetics may make very little insulin and require injections. Any insulin that the body does make will be reflected in their C-peptide level; therefore, the C-peptide test can be used to monitor beta cell activity and capability over time and to help your doctor determine when to begin insulin treatment.

High levels of C-peptide generally indicate high levels of endogenous insulin production. This may be a response to high levels of blood glucose caused by glucose intake and/or insulin resistance. (With insulin resistance, the body’s cells do not use insulin normally to transport glucose inside the cell. The cells become “starved for glucose,” interpret that as a lack of insulin, and signal the body to make more.) High levels of C-peptide also are seen with insulinomas (insulin-producing tumors) and may be seen with hypokalemia, pregnancy, Cushing’s syndrome, and renal failure.

Low levels of C-peptide are associated with low levels of insulin production. This can occur when insufficient insulin is being produced by the beta cells or when production is suppressed by exogenous insulin or with suppression tests that involve substances such as somatostatin.

Even though they are produced at the same rate, C-peptide and insulin leave the body by different routes. Insulin is processed and eliminated mostly by the liver, while C-peptide is removed by the kidneys. Since the half-life of C-peptide is about 30 minutes to insulin’s 5 minutes, normally there will be about 5 times as much C-peptide in the bloodstream as insulin.
 
Thanks for all of the replies - I do appreciaete them. As I originally thought, it seems that the only way to find out if I have high insulin resistance, or if I'm simply not making enough insulin, can only be determined by carrying out a C-Peptide test...

Shame there's not more info on this - because it seems to me that if every Type 2 knew what was causing their high BG they could tailor their treatment.

I know not all Type 2's are insulin resistant...
 
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