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insulin
- Thread starter mistee71
- Start Date
mistee71
Well-Known Member
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- FOOTBALL. MY husband is a sports fanatic and watches everything. Most i can put up with just not football.
dont matter now. i found out.
An insulin analog is an altered form of insulin, different from any occurring in nature, but still available to the human body for performing the same action as human insulin in terms of glycemic control. Through genetic engineering of the underlying DNA, the amino acid sequence of insulin can be changed to alter its ADME (absorption, distribution, metabolism, and excretion) characteristics. Officially, the U.S. Food and Drug Administration (FDA) refers to these as "insulin receptor ligands", although they are more commonly referred to as insulin analogs.
These modifications have been used to create two types of insulin analogs: those that are more readily absorbed from the injection site and therefore act faster than natural insulin injected subcutaneously, intended to supply the bolus level of insulin needed after a meal; and those that are released slowly over a period of between 8 and 24 hours, intended to supply the basal level of insulin for the day. Insulin analog was first manufactured by Eli Lilly and Company.
An insulin analog is an altered form of insulin, different from any occurring in nature, but still available to the human body for performing the same action as human insulin in terms of glycemic control. Through genetic engineering of the underlying DNA, the amino acid sequence of insulin can be changed to alter its ADME (absorption, distribution, metabolism, and excretion) characteristics. Officially, the U.S. Food and Drug Administration (FDA) refers to these as "insulin receptor ligands", although they are more commonly referred to as insulin analogs.
These modifications have been used to create two types of insulin analogs: those that are more readily absorbed from the injection site and therefore act faster than natural insulin injected subcutaneously, intended to supply the bolus level of insulin needed after a meal; and those that are released slowly over a period of between 8 and 24 hours, intended to supply the basal level of insulin for the day. Insulin analog was first manufactured by Eli Lilly and Company.
phoenix
Expert
- Messages
- 5,671
- Type of diabetes
- Type 1
- Treatment type
- Pump
Well I was writing my answer but had to stop midway. I'll post it anyway!
Insulin from most animals is fairly similar and can be used in humans. For many years people used purified animal insulin from cows or pigs. ( there are several people on this forum who continue to use animal insulin).
Following the discovery of the DNA sequence of insulin ( http://en.wikipedia.org/wiki/Frederick_Sanger
) it became possible to create and grow insulin in the laboratory. This has exactly the same DNA pattern as insulin from a human pancreas and so is called human insulin... though not from humans :lol:
.
Human or animal insulin can be regular which is relatively short acting. The insulin manufacturers also developed insulins that lasted longer in the body by including additives that slow/delay their action.
Analogue insulin is. also made in the laboratory. In this type of insulin instead of adding something to change the action of the insulin, changes have been made to the genetic sequence. Some insulins have been developed that work very rapidly and are meant to be injected on eating and others that are meant to provide a continuous background insulin.
Insulin from most animals is fairly similar and can be used in humans. For many years people used purified animal insulin from cows or pigs. ( there are several people on this forum who continue to use animal insulin).
Following the discovery of the DNA sequence of insulin ( http://en.wikipedia.org/wiki/Frederick_Sanger
) it became possible to create and grow insulin in the laboratory. This has exactly the same DNA pattern as insulin from a human pancreas and so is called human insulin... though not from humans :lol: .
Human or animal insulin can be regular which is relatively short acting. The insulin manufacturers also developed insulins that lasted longer in the body by including additives that slow/delay their action.
Analogue insulin is. also made in the laboratory. In this type of insulin instead of adding something to change the action of the insulin, changes have been made to the genetic sequence. Some insulins have been developed that work very rapidly and are meant to be injected on eating and others that are meant to provide a continuous background insulin.
lowthian20
Member
- Messages
- 11
- Type of diabetes
- Type 1
Hi
Not a clue if posted in the correct section but here goes.
i was taken off Aprida insulin about 2 months ago as apparently they have run out of stock. I was then put onto Humalog. Everything was ok at first with this insulin then over the last couple of weeks my BG have gone haywire with high readings. For example this morning before breakfast my BG was 8.8, had two slices of toast gave myself 8u of insulin. Tested before lunch and bloods were 17.5 with keytone alerts
Any clues would be welcome
Not a clue if posted in the correct section but here goes.
i was taken off Aprida insulin about 2 months ago as apparently they have run out of stock. I was then put onto Humalog. Everything was ok at first with this insulin then over the last couple of weeks my BG have gone haywire with high readings. For example this morning before breakfast my BG was 8.8, had two slices of toast gave myself 8u of insulin. Tested before lunch and bloods were 17.5 with keytone alerts
Any clues would be welcome
