Some interesting comments from the article ...
The 2011 Hunt 2 study, one of the most recent and largest, followed 52,000 men and women in Norway aged 20-74 with no pre-existing heart disease, for 10 years.
The results for women were crystal clear. The lower a woman’s total cholesterol, the greater her risk of dying, either of heart disease or anything else, including cancer. This reflects findings in previous studies.
For men, high cholesterol was associated with heart disease and death from other causes. But so, too, was low cholesterol — below 5mmol/l. Again, this is only an association, not a causal link. A range of between 5mmol/l and 7mmol/l was the optimum level. Guess what? This is already the national average. In addition, numerous studies have linked high cholesterol levels with increased longevity in the elderly.
My cholesterol was 4.8, yet I was called in to see my GP who suggested I take statins. Lowering cholesterol below 5 actually raises all cause mortality, especially in women. The real reason for heart disease and strokes is inflammation in the arteries and this is caused by eating too many carbs (e.g. sugar) which causes blood glucose spikes. Cholesterol is a mechanism the body uses to repair damage caused by inflammation as a result of easting too much carbs. Cholesterol is not the cause of heart disease, but a marker that something may be wrong.
Fat in diet has been the scapegoat for too long, whereas it is the high carbs people eat that is causing a rash of diseases including heart disease, cancer and Alzheimers.
Indeed.
From my point of view, as I've written, I have been told to take Statins by a vascular surgeon for a particular problem. What amazes me is that two medics in the same discipline have such diametrically opposed views. Incidentally, this is the first time I've seen someone from the same field expressing these views. The point being that my specialist is vehemently sticking to the Statin route and he, like other HCPs, disappeared into the depths of the hospital without offering any real explanation. I am not thick (very) and deserve proper reasoning. OK, appointment times are strictly limited but at least I could be directed to online or print media where I can learn the balanced facts - and not just diluted national guidelines.
I want to make the best choice for me - I'm sure we all do - but this conflict is difficult when there is so much at stake for all of us.
Whilst I tend to agree with your statements regarding heart disease etc being directly caused by high carb intake, I would add that the science has not proven that yet, and the jury is still out. The statistics regarding mortality links to total cholesterol are very interesting, but again, the evidence that a LC diet helps reduce total cholesterol or improve 'good' cholesterol is based on anecdotal evidence, and is not yet firmly established, Again, the mantra that sat fat is no longer the bogeyman is based on the findings of one study that was a meta data analysis, so is not exactly gold plated eitherSome interesting comments from the article ...
The 2011 Hunt 2 study, one of the most recent and largest, followed 52,000 men and women in Norway aged 20-74 with no pre-existing heart disease, for 10 years.
The results for women were crystal clear. The lower a woman’s total cholesterol, the greater her risk of dying, either of heart disease or anything else, including cancer. This reflects findings in previous studies.
For men, high cholesterol was associated with heart disease and death from other causes. But so, too, was low cholesterol — below 5mmol/l. Again, this is only an association, not a causal link. A range of between 5mmol/l and 7mmol/l was the optimum level. Guess what? This is already the national average. In addition, numerous studies have linked high cholesterol levels with increased longevity in the elderly.
My cholesterol was 4.8, yet I was called in to see my GP who suggested I take statins. Lowering cholesterol below 5 actually raises all cause mortality, especially in women. The real reason for heart disease and strokes is inflammation in the arteries and this is caused by eating too many carbs (e.g. sugar) which causes blood glucose spikes. Cholesterol is a mechanism the body uses to repair damage caused by inflammation as a result of easting too much carbs. Cholesterol is not the cause of heart disease, but a marker that something may be wrong.
Fat in diet has been the scapegoat for too long, whereas it is the high carbs people eat that is causing a rash of diseases including heart disease, cancer and Alzheimers.
Bit like the pro statin studies then... sorry couldn't resist...it does not have the rigorous scientific study behind it to provide irrefutable evidence,
Blatant bit of hijacking there, BB..... At least the statin science has been largely debunked now.. I found evidence in one study that their conclusion did not reflect the data at all. Whereas the evidence for higher mortality risk being linked to low cholsterol is actually reported in a couple of studies now, The Harvard Nurses study is a large scale study, and it is still ongoing, so is relatively long term too. It is also forming the basis of a load of independent researchers using the data to discover other trends, so has independent oversight in a way. There is also the Australian study that analysed post mortem data from CVE events vs LDL levels.Bit like the pro statin studies then... sorry couldn't resist...
There is also the blatent attempts at marketing statins as a cure all for a whole raft of diseases, such as rheumatism, Parkinsons, and other seemingly totally unrelated to CVE., such as some cancersBased on the pro-statin research paid for by the drug makers, about 150 people need to take statins for each person that benefits from them when they are given out according to the NICE guidelines. A 10 minutes walk each day gives a larger reduction in risk.
But with much more advanced tests then GP have access to, it is possible to predict who will benefit from statins. It is becoming very clear that any benefit is not from reducing total cholesterol.
It used to be believed that LDL causes arterial plaque buildup and inflammatiom. Recent science thinking is beginning to show that other particles, such as sLDL and trigs are more likely candidates, and that LDL is an essential endocrine function that transports lipids in the blood, and is not the bad guy at all. Bit like blaming petrol for causing fuel blockages and dirty carburettors, when it is the impurities in it causing those problems.Given that is seem satins reduce inflammation, I can see how over a very large dataset there would be a small reduction in rheumatism and Parkinson’s for people taking them.
But very low carb (keto) diets reduce inflammation a LOT more…….
A very high level of carbs increases inflammation …..
No one yet has a large dataset for LCHF, so we will have to wait for a few years for proof about rheumatism and LCHF.
I have seen no evidence of proven benefit re statins.
Going off on a tangent from the original thread. However, just to clarify from a couple of relatives' experience. For the 'elder generation', it tends to be radiotherapy and hormone treatment to put the cancer into remission exactly for the reason that you say that something else will get you first!Ditto.
That applies to other stuff too. Cancer screening is one such area. It has been abundantly proved that it increases survival time between diagnosis and death. But in many cases that is entirely because the cancer has been detected earlier. In those cases people die at pretty much the same age that they would have, even if the cancer had been found later.
Of course it varies quite a lot, depending on the type of cancer. But as a man, I have pretty much decided that (now that I am in my 60s) prostate screening is not for me. It is hard to get them to stop running PSAs, but if they came back and said yours is elevated, I hope I would have the guts to refuse the biopsy. I have heard so much about how it ruins many men's quality of life (and personally known some cases) and how relatively rare the aggressive form of the disease is.
It is age-dependent. If it happened to me in my 20s or 30s that would be a different matter. But if they found prostate cancer at my age, there is an overwhelming chance that something else will kill me before prostate cancer does. Or, that the cancer would kill me, but in ripe old age. (It killed two of my close relatives, but they were both in their mid-90s).
Of course there are likely some men on this forum whose life was saved by early detection of prostate cancer and the subsequent surgery.
Sorry, off-topic but actually a similar issue.
And 55 per cent said they would not take statins themselves or recommend them to a relative, based on the proposed new guidelines."
I have been told to take Statins by a vascular surgeon for a particular problem. What amazes me is that two medics in the same discipline have such diametrically opposed views.
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