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Irritable Bowel Syndrome And Type 2 Diabetes
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<blockquote data-quote="willmax" data-source="post: 1860436" data-attributes="member: 157106"><p>I have had type 1 diabetes for 68 years. For a long time I struggled with constipation. However, it is now widely accepted in the research literature that long term treatment for diabetes destroys cells called Golgi interstitial cells in the gut wall. The Golgi interstitial cells are intermediate in form between smooth muscle and neurones. The Golgi interstitial cells, about which even my diabetic consultant was ignorant, control the rhythmic motility of the gut wall called peristalsis. Peristalsis moves the gut contents toward the anus. So loss of Golgi interstitial cells disrupts peristalsis and results in constipation. I have found 2 Senna tablets before bed each night and 5ml of lactulose solution after each meal helpful to return to a normal gut routine.</p></blockquote><p></p>
[QUOTE="willmax, post: 1860436, member: 157106"] I have had type 1 diabetes for 68 years. For a long time I struggled with constipation. However, it is now widely accepted in the research literature that long term treatment for diabetes destroys cells called Golgi interstitial cells in the gut wall. The Golgi interstitial cells are intermediate in form between smooth muscle and neurones. The Golgi interstitial cells, about which even my diabetic consultant was ignorant, control the rhythmic motility of the gut wall called peristalsis. Peristalsis moves the gut contents toward the anus. So loss of Golgi interstitial cells disrupts peristalsis and results in constipation. I have found 2 Senna tablets before bed each night and 5ml of lactulose solution after each meal helpful to return to a normal gut routine. [/QUOTE]
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