Reply to Thread

Guest, we'd love to know what you think about the forum! Take the Diabetes Forum Survey 2025 »

Message: <blockquote data-quote="Oldvatr" data-source="post: 2020199" data-attributes="member: 196898">One problem I have with many reversal theories, even Jason Fung, is that it seems they use a very simple model of Insulin Resistance.  My research into what the endocrinologists say in their gobbledegook way is that there is at least two seperate forms of Insulin Resistamce.  Mitochondrial (or muscle cell) and adipose (adipocytes)  These tissues store energy in different ways.  Muscle cells store glucose and water as glycogen.  The liver also stores it as glycogen, but also stores triglycerides created by lipids from fat or created by the body from recycled glucose.  The chemical locks that insulin controls in the storage process has different chemical markers, and so the two types of storage require slightly different keys to open them and allow storage.  So it is possible to have different forms or IR that affects one or the other, or both.It seems that T2D has an early start with the muscle form of IR.  This reduces glucose storage in muscles.  Over time, this seems to lead on to adipose IR as fat deposits grow around the liver and pancreas.  This then leads to the familiar Metabolic Syndrome of T2D.  So TOFU T2D seem to be mainly muscle IR but still diabetic.  I was this for about 10 years, then ballooned in the midriff area and got much worse.True remission (IMO) requires removal of both adipose fat  from liver and pancreas, but also reduction of muscle IR too.  I think Newcastle Diet and Fung tackle the adipose psrt, but may not remove muscle IR.  I think this is why I must continue to use LC diets.</blockquote>

Verification

Top Bottom

Search

Search

Reply to Thread