- Messages
- 4,445
- Location
- Suffolk, UK
- Type of diabetes
- Type 2
- Treatment type
- Tablets (oral)
- Dislikes
- Diet drinks - the artificial sweeteners taste vile.
Having to forswear foods I have loved all my life.
Trying to find low carb meals when eating out.
Apologies because this is a bit of a place holder before I forget.
When you are running on glucose there is a control mechanism from the pancreas where glucagon tells the liver to release glucose, and insulin tells the fat cells to mop up glucose. Some people around here don't have that balance working properly and are thus diabetic.
When you are running on ketones the liver switches over from producing glucose to producing ketones, however what is the comparable mechanism to insulin/glucagon to keep the correct level of ketones in the blood and prevent ketoacidosis (the ketogenic version of hyperglycemia)?
The fats are presumably transported from the fat cells through the blood to the liver to be converted into ketones. Are they transported as cholesterol (which I understand is the normal way to shift fat through the blood stream)?
Just pondering if the mechanism to transport fats to the liver when you are LCHF and possibly in ketosis could lead to higher cholesterol if the control mechanism isn't working properly.
Sort of the ketosis version of diabetic. Ketobetic?
Could explain why some people see a drop in cholesterol when going LCHF and others see a rise. Could also explain why some people have familial high cholesterol (hypercholesterplemia).
Further investigation needed, but I thought I would capture this so I remember.
When you are running on glucose there is a control mechanism from the pancreas where glucagon tells the liver to release glucose, and insulin tells the fat cells to mop up glucose. Some people around here don't have that balance working properly and are thus diabetic.
When you are running on ketones the liver switches over from producing glucose to producing ketones, however what is the comparable mechanism to insulin/glucagon to keep the correct level of ketones in the blood and prevent ketoacidosis (the ketogenic version of hyperglycemia)?
The fats are presumably transported from the fat cells through the blood to the liver to be converted into ketones. Are they transported as cholesterol (which I understand is the normal way to shift fat through the blood stream)?
Just pondering if the mechanism to transport fats to the liver when you are LCHF and possibly in ketosis could lead to higher cholesterol if the control mechanism isn't working properly.
Sort of the ketosis version of diabetic. Ketobetic?
Could explain why some people see a drop in cholesterol when going LCHF and others see a rise. Could also explain why some people have familial high cholesterol (hypercholesterplemia).
Further investigation needed, but I thought I would capture this so I remember.