Mate go Keto and you'll never need to inject insulin.....

O_DP_T1 said:

...so just been talking to my project manager who's been on this Keto diet thing for a month and he say's he's been watch some internet TV show on Keto and apparently there's a woman who has stopped taking insulin due to a successful Keto diet. He went on to say that I should give it a go and slowly stop taking insulin.

I did try and explain that as someone who's been T1 for 40 years there's noway I can go without insulin as my body no longer produces any. I tried to explain that the case he referred to might have been T2 who needed very little insulin and the extremely low carb Keto diet may have eliminated that need. But he was adamant she was a T1, at which point I just did my NovoRapid and started eating chicken and rice.

Seriously where do these people come from......

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O_DP_T1 said:

But he was adamant she was a T1

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ringi said:

Maybe she was Type 1.5, or Type2 but had been told by a doctor she was type1. Given that it is common for doctors to assume type1 without an antibody (or cpeptide) test, we can't say that someone who believes themselves to be type1, would not be able to stop all insulin on a keto diet.

(Also, there has been a few proven cases of people who tested positive for the anti-bodies who reversed their diabetes with keto, but they had very recently been diagnosed and are clearly the exception..)

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ringi said:

(Also, there has been a few proven cases of people who tested positive for the anti-bodies who reversed their diabetes with keto, but they had very recently been diagnosed and are clearly the exception..)

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Draco16 said:

This is very encouraging, can you provide a link to read on this please.

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kev-w said:

I don't ever remember having an antibody test so believe I'm type1 but know I can't stop taking insulin whatever diet I eat, and I think those cases you call proven will have been due to the honeymoon period experienced by t1s where the pancreas can stutter along for a while if carbs are sacrificed, so it's more delayed than reversed, in my opinion of course.

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ringi said:

But what we do know is that a lot of people with type1 find they get much better control with very low carb diet regardless of the very low possibility of 'reversing' type1 with such a diet.

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Fairygodmother said:

https://www.med.wisc.edu/news-and-events/2013/july/gene-therapy-for-type-1-diabetes/

Diabetes blood test 'could mean end to daily insulin jabs'http://www.bbc.co.uk/news/uk-scotland-44144678

Two articles which cover reversal of T1.

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Fairygodmother said:

Don’t knock the research being carried out in Wisconsin @kev-w; the results may not happen for a good few years, and it may not work at all, or if it does then only a few may benefit, but at least they’re having a go!

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The study, reported in the June 27, 2013, issue of the journal PLOS ONE, describes a small sequence of DNA that, when injected into the veins of diabetic rats, create insulin-producing cells that help normalize blood sugar levels and perfect the regulation of glucose metabolism. It is the first known study to demonstrate how a DNA-based insulin gene therapy has the potential to treat type 1 diabetes.

“Even we were surprised that a single injection could provide perfect glycemic control for up to six weeks,” says Hans Sollinger, the Folkert O. Belzer Professor of Surgery at the UW School of Medicine and Public Health. “After receiving the therapy, the diabetic rats had insulin and glucose levels that resembled exactly what you would find in healthy animals.”

The DNA sequence of the therapy works by sensing an increase in glucose concentrations in the body (such as after a meal) and then, with the help of a glucose inducible response element (GIRE), prompts the injected DNA to produce insulin, similar to the way normal pancreatic cells do. But instead of targeting pancreatic cells, the therapy exclusively targets the liver.

“We chose the liver as the ideal target for this therapy because of its ability to regenerate,” says Sollinger. “In order for the therapy to be effective, the DNA needs to enter and attach to millions of cells, so the liver’s ability to replace dead cells was an obvious advantage. The treatment essentially makes the liver function like a mini-pancreas.”

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Early evidence of the potential success of the therapy inspired Sollinger and one of his colleagues, Tausif Alam, to start Insulete Inc., a private research firm dedicated to improving the treatment of type 1 diabetes. Insulete, which stands for “insulin obsolete,” developed and patented the minicircle DNA used to treat the diabetic rats. The Wisconsin Alumni Research Foundation (WARF) owns the patent on GIRE and leases it to Insulete Inc. for their ongoing research.

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