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Type 2 Diabetes
Metformin and Anemia?
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<blockquote data-quote="Mars1946" data-source="post: 1160018" data-attributes="member: 297770"><p>Hi Galja</p><p>Thanks for the links to the NCBI. This article describes the problem.</p><p>In the article and what your doctor has informed you about B12 is not complete information about B12.</p><p>By the adult people the organisms total amount of cobalamin B12 is about 5 - 10 mg. One part of this depots is in the liver and the another is in the CNS (the brain), but the depots in the CNS is difficult to be mobilized. The daily consumption of cobalamin in the body is 0.1% of the depots amount, so cobalamin deficient develops slowly and sneaking over many years. The Cobalamin, B12 has an enterohepatic circulation in the body, i.e. it is excreted by the bile and enters in the duodenum, where in the ileum is again absorb. In the tissues cells cobalamin has function as coenzyme. B12 deficiency can develop of different reasons. I am talking here about deficiencies as side effects/ complications of using Metformin. The cobalamin from the depot is not ****** out , but it is excreted trough the bile in the facet (****) i.e. it is not excreted by the kidney.</p><p>The tablets I am using has the name: "Betolvex 1 mg, cyanocobalamin". Ask your doctor or pharmacist for side effect using this medication.</p><p>PS About E-mailing you activate the envelope on the upper right corner and activate the green bottom. You will be guided for the remnant.</p></blockquote><p></p>
[QUOTE="Mars1946, post: 1160018, member: 297770"] Hi Galja Thanks for the links to the NCBI. This article describes the problem. In the article and what your doctor has informed you about B12 is not complete information about B12. By the adult people the organisms total amount of cobalamin B12 is about 5 - 10 mg. One part of this depots is in the liver and the another is in the CNS (the brain), but the depots in the CNS is difficult to be mobilized. The daily consumption of cobalamin in the body is 0.1% of the depots amount, so cobalamin deficient develops slowly and sneaking over many years. The Cobalamin, B12 has an enterohepatic circulation in the body, i.e. it is excreted by the bile and enters in the duodenum, where in the ileum is again absorb. In the tissues cells cobalamin has function as coenzyme. B12 deficiency can develop of different reasons. I am talking here about deficiencies as side effects/ complications of using Metformin. The cobalamin from the depot is not ****** out , but it is excreted trough the bile in the facet (****) i.e. it is not excreted by the kidney. The tablets I am using has the name: "Betolvex 1 mg, cyanocobalamin". Ask your doctor or pharmacist for side effect using this medication. PS About E-mailing you activate the envelope on the upper right corner and activate the green bottom. You will be guided for the remnant. [/QUOTE]
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