I am currently on 3 * 500 mg - two in the morning and one in the evening. My latest HbA1c was 47/6.4 which is just inside pre-diabetic (just below diabetic). This has been pretty consistent although I know I could do better. My eGFR was down to 58 mL/min which is a sign of kidneys not doing their job properly. Although eating a lot of protein and not drinking a lot of water and exercising quite a bit can all skew the figures. Anyway, my DSN advised dropping to 2 * 500 mg Metformin because my HbA1c was consistently in a good range (from her point of view) and it was more important to address the possible kidney issues. Noting that my eGFR has been that low before and has also been up in the '80s so go figure. Anyway, happy to drop the Metformin dosage but wondering if I should go the whole hog and come off Metformin completely for a little (in a phased manner). Metformin has many good aspects, but dodgy kidneys might be more of an issue than a slightly dodgy pancreas and harder to fix. Has anyone else had similar issues with kidney function and Metformin?