Metformin and micro vascular complications

Watching this thread as I'm interested in the merits of Metformin with T1D. It seems like a fair few clinics offer this drug to their T1 patients.

Hope you get an answer soon @novorapidboi26

Have you guys seen this thread...
http://www.diabetes.co.uk/forum/threads/type-1-and-metformin.29433/

bulkbiker said:

Have you guys seen this thread...
http://www.diabetes.co.uk/forum/threads/type-1-and-metformin.29433/

Click to expand...

Thanks for that. I took from there that metformin can play a role in reducing DP, so I'm interested. Hopefully hear some positive news from a T1D with DP who is taking metformin to help/beat it...

http://www.defeatdiabetes.org/vitamin-c-stops-blood-vessel-damage-in-type-1-diabetes/

For the last few months, I've been taking high doses of vitamin C powder (L-ascorbic acid) as it has various properties.

antioxidant
antiviral
antitoxin
antimicrobial

I take 5gm morning and evening.
In a talk on YouTube (link below) Thomas Levy, a proponent of megavitamin therapy, points out that diabetes is inversely associated with vitamin C levels, which would suggest we could all benefit from it. He relates various conditions to localised scurvy e.g. atherosclerosis = arterial scurvy, osteoporosis = bone scurvy, heart attack = heart scurvy.

It appears that vitamin C improves the elasticity of capillaries, and therefore lessens their fragility. It appears to target sorbitol (https://www.ncbi.nlm.nih.gov/pubmed/7963139)
More can be found on Dr Saul's website (http://www.doctoryourself.com/diabetes.html)

There are other YT videos by Thomas Levy and Suzanne Humphries

HTH
Geoff

I thought metformin was prescribed to reduce insulin resistance and metabolic syndrome in people with a BMI over 27, regardless of type of diabetes. I was never on it though, as my GP at diagnosis thought I wouldn't benefit from it as I hadn't any particular signs of insulin resistance or metabolic syndrome nor did I fit the BMI figure.

It is often prescribed to reduce insulin resistance in women with PCOS.

I have never heard of metformin as a help for micro vascular problems but then I'm not a doctor.