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Metformin and Vitamin B12 deficiency
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<blockquote data-quote="cugila" data-source="post: 151907" data-attributes="member: 15325"><p>Denise.</p><p>It's not that the lack of B12 upsets your stomach as it is the Metformin that can upset your stomach. Metformin has the side effect where it can deplete the body's reserves of Vit B12.</p><p></p><p>The levels are shown in ng/l. (nanagrams per litre). All labs use slightly different ranges, the one I use has the range from 197 - 866. So your level of 283 would be classed as within range but at the lower end of the scale. Just as mine was, which required treatment. My level was lower than yours at 228. </p><p></p><p>Was a treatment option discussed at all ? </p><p></p><p>I had Cancer treatment and I am also on Metformin (2 x 500 once daily). After my treatment blood tests showed I had low levels of B12. This can be rectified quite easily by either having a course of injections or taking Cyanocobalamin Tablets. My levels are now back to a more normal level although still a little lower than I want, I feel better for having them. No fatigue. </p><p></p><p>I chose the daily tablets as I already inject twice daily and wasn't looking forward to any more injections. There is no need for the Metformin to be stopped unless you truly cannot tolerate them, there is always the slow release versions, MR/SR.</p><p></p><p>Talk to your GP about it.</p><p></p><p>Ken</p></blockquote><p></p>
[QUOTE="cugila, post: 151907, member: 15325"] Denise. It's not that the lack of B12 upsets your stomach as it is the Metformin that can upset your stomach. Metformin has the side effect where it can deplete the body's reserves of Vit B12. The levels are shown in ng/l. (nanagrams per litre). All labs use slightly different ranges, the one I use has the range from 197 - 866. So your level of 283 would be classed as within range but at the lower end of the scale. Just as mine was, which required treatment. My level was lower than yours at 228. Was a treatment option discussed at all ? I had Cancer treatment and I am also on Metformin (2 x 500 once daily). After my treatment blood tests showed I had low levels of B12. This can be rectified quite easily by either having a course of injections or taking Cyanocobalamin Tablets. My levels are now back to a more normal level although still a little lower than I want, I feel better for having them. No fatigue. I chose the daily tablets as I already inject twice daily and wasn't looking forward to any more injections. There is no need for the Metformin to be stopped unless you truly cannot tolerate them, there is always the slow release versions, MR/SR. Talk to your GP about it. Ken [/QUOTE]
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