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Metformin - Stopped Working ?

Discussion in 'Metformin/Biguanides' started by ruts66, Jul 5, 2016.

  1. ruts66

    ruts66 Type 2 · Newbie

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    Hi Guys,

    Newbie to the forum but have used the website as a valuable resource since first diagnosed T2 in April 2014.

    June 2014, GP prescribed Metformin 2 x 500mg/day after I failed to significantly reduce my BG levels through diet and exercise alone. Normal BG levels restored and no major side effects. Quarterly A1c tests satisfactory, until now...

    5 weeks ago at my latest review my A1c result prompted a doubling of Metformin to 4 x 500mg/day. I'm currently experiencing symptoms familiar to pre-diagnosis (forgetful, lethargic, falling asleep after meals, burning/itching feet, etc...). I have an Accu-Chek Mobile testing device which last night recorded a reading of 11.5mmol/L 90 minutes after dinner and this morning a reading of 8.0mmol/L pre-breakfast. Both are about 3 points higher than when I last felt okay.

    - Typically, is there a point where Metformin loses its efficacy in T2 despite a higher dosage ?

    - What new meds might I expect my GP to recommend at my next appointment ?

    - What 'hero' foods might I try to improve my mood (depression) in the absence of complex carbs ?

    Thank you in advance,


    ruts
     
  2. Osidge

    Osidge Type 2 · Well-Known Member
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    Metformin would not work if you were not producing insulin or would work less well if you had a reduced insulin production. Your GP can prescribe various medications such as liraglutide, exenatide and dapagliflosin.

    Hope all goes well for you.

    Regards

    Doug
     
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  3. Enclave

    Enclave Type 2 (in remission!) · Well-Known Member
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    - What 'hero' foods might I try to improve my mood (depression) in the absence of complex carbs ?

    Could you tell us what you are eating in a typical day ...
     
  4. Osidge

    Osidge Type 2 · Well-Known Member
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    I gave up sugary foods at diagnosis so have not had puds, sweets or any food with glucose, sucrose, fructose etc. since then. I tend to eat bread, pasta, rice and below the ground veg only very occasionally. I enjoy meats, fish, eggs, salad and above the ground veg. I have some days when I replace 2 meals with Tesco meal replacement drinks. That, along with 500mg Metformin 3 times a day does it for me. The drinks help me as I also have Parkinson's Disease and slow motility.

    Regards

    Doug
     
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