I am on 4 a day, but I am on the slow/modified release type - before, I had serious discomfort but I responded well to these which is just as well, as I also have to take Sitagliptin and Dapagliflozin for the diabetes, 75 mg levothyroxine for under active thyroid 50 mg Azathioprine and 3 mg prednisolone (reducing) for Pemphigoid and omeprazole to prevent stomach problems from the prednisolone plus once a week Alendronic acid to prevent osteoporosis from prednisolone. I got polymyalgia (pmr) about 3 years ago, and was put on a high dose of prednisolone which played havoc with previously good control. They reduced me rapidly because of the diabetes and that seemed to trigger the Pemphigoid so I had to go back to a high dose plus the Azathioprine. I had never heard of PMR or Pemphigoid before I got them. Oh, and a statin. Pick me up, and I rattle, folks.