Autoantibody formation is a precursor of type 1 diabetes. This study revealed that methionine levels in the blood of children who form these antibodies at an early age are fifty per cent lower than those in individuals who develop antibodies in puberty or not at all.
Methionine is an essential amino acid that must be ingested through food because the body cannot make it itself. However, diet does not seem to be the only key factor here.
Researchers assume that various trigger mechanisms determine whether islet autoimmunity occurs and, if so, at what age. Methionine, they believe, should therefore be considered as a biomarker for type 1 diabetes.
The team led by Prof. Anette-Gabriele Ziegler will now examine the biological mechanisms underlying the various trigger mechanisms for islet autoimmunity with a view to developing primary prevention strategies and immune therapies that can be used in early childhood.
http://www.biosciencetechnology.com...ent-mechanisms-trigger-type-1-diabetes-autoi/
Methionine is an essential amino acid that must be ingested through food because the body cannot make it itself. However, diet does not seem to be the only key factor here.
Researchers assume that various trigger mechanisms determine whether islet autoimmunity occurs and, if so, at what age. Methionine, they believe, should therefore be considered as a biomarker for type 1 diabetes.
The team led by Prof. Anette-Gabriele Ziegler will now examine the biological mechanisms underlying the various trigger mechanisms for islet autoimmunity with a view to developing primary prevention strategies and immune therapies that can be used in early childhood.
http://www.biosciencetechnology.com...ent-mechanisms-trigger-type-1-diabetes-autoi/
