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Mixed insulins

kegstore

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OK I know being on a pump for 5 years means I'm quite out of touch with MDI therapy, but can someone explain to me the advantages of this type of insulin and associated regime eg Novomix, mixtard etc. From my blinkered view I only see disadvantages, especially since the advent of basal/bolus, hence my question! TIA :)
 
Kegstore
It depends ultimately on what your goals are, what routine you prefer etc. i am on Mixtard, but dont want to be. As someone who has adjusted diet since day 5 and also likely still in honeymoon (7 months and counting :shock: ) my doses are usually only 12 or 13 TDD. Consequently Endo thinks too dangerous to titrate to basal/bolus at this point, though agrees with my being on it as he feels it is the cornerstone of modern diabetes management (though some would of course say pump is this).

The benefits are a matter of perspective - only 2 injections per day, good for weight gain if you need it, easy enough profile to mark in terms of times to watch for hypos. Also suits you if you have a fixed routine, regular eating times etc. Novo market it for type 2's and report good A1c results (though they would, of course!). It is of course used a lot for children and also type 1's

Though, christ knows why

Its not great for much else though - lack of flexibility, cant correct high bg, cant dose adjust, for food changes, not great for PP in my opinion (though spikes happen with all insulins anyway). It does cause weight gain and anecdotally when unwell given it can be dose adjusted to bring bg down, more likely to lend itself to either dangerously high or dangerously low bg. IMHO its a regime that works if you are very strict, as I am. Otherwise, its pants!

Still, its keeping me alive and my second A1c was 5.1 so maybe I shouldnt diss the Mix :lol:
 
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