Never had muscle-weakness from it, but do sometimes experience pins 'n' needles and/or shooting pains.
Not on any medication so can't speak to that, but I find the shooting pains only tend to happen these days if I've overdone the sugar e.g if I have too much dessert etc. after an already heavy-carb meal. The pins 'n' needles tend to come more after a fasted-state i.e in the morning, after not having eaten for about 12 hours, or so.
These symptoms were at their peak at the beginning of this year when my average dailyFBGI was circling around 18 mini-moles. Fortunately, these days, despite still having higher sugars (Though much less than before), I experience these symptoms much less often (The shooting pains are now extremely rare).