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New method of treating type 1 diabetes proposed by US researcher
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<blockquote data-quote="ringi" data-source="post: 2122969" data-attributes="member: 410240"><p>This blood vessel is easy to access in dogs, but very hard to access in people. Hence so much research is done in dogs. </p><p></p><p>The pancreas also gets the blood directly from the digestive system, hence can sence BG before it gets to rest of the body. So can preemptively release inslin to the liver when BG is about to increase. There are additional messaging systems from the digestive system to the pancreas, these are not yet well understood. </p><p></p><p>At times of rapid increasing BG, the inslin concentration in the liver is many times higher then the rest of the body. This happens when carbs are eaten. The liver then stops releasing glocose and starts taking up glocose from the blood.</p><p></p><p>In type2 the liver does not correctly respond to this high concentration of inslin, in type1 there is no way to direct a high concentration of inslin at the liver.</p><p></p><p>When people without diabetes eats a very low carb meal the inslin concentration is much the same over the complete body and the liver does much less.</p></blockquote><p></p>
[QUOTE="ringi, post: 2122969, member: 410240"] This blood vessel is easy to access in dogs, but very hard to access in people. Hence so much research is done in dogs. The pancreas also gets the blood directly from the digestive system, hence can sence BG before it gets to rest of the body. So can preemptively release inslin to the liver when BG is about to increase. There are additional messaging systems from the digestive system to the pancreas, these are not yet well understood. At times of rapid increasing BG, the inslin concentration in the liver is many times higher then the rest of the body. This happens when carbs are eaten. The liver then stops releasing glocose and starts taking up glocose from the blood. In type2 the liver does not correctly respond to this high concentration of inslin, in type1 there is no way to direct a high concentration of inslin at the liver. When people without diabetes eats a very low carb meal the inslin concentration is much the same over the complete body and the liver does much less. [/QUOTE]
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