• Guest - w'd love to know what you think about the forum! Take the 2025 Survey »

New to Tresiba - Flexibility?

golden oldie said:
I was told by the diabetic nurses that Tresiba doesn't flatline, it goes up and over in a loop, then down again. I'm having problems with going low at bedtime and high first thing in the morning, which bears that out. I have it before breakfast. Going to talk to someone about it asap
Click to expand...
Yet ivwas told it flat lined?! Has the whiff of when analog insulins 1st made an appearance, no one actually knows what they do.
 
I am very confused regards your way of Taking Tresiba @kimberleyanneb I also take Tresiba which I love. If I alter my dose it takes about 3-4 days to show negligible benefit. So changing the dose regularly would be a strange thing to do. Also why take notice of a prior blood test before taking. Surely that blood test relates to recent food and bolus doses and should not influence a basal dose.
 
I was on Lantus, then Levemir, then Tresiba, and finally Omnipod pump.
Lantus is quite short acting, and acts as a short acting insulin if injected accidentally into a vein.
Levemir is quite short acting, too, but isn’t sensitive to injecting into veins/capillaries.
Tresiba is a really long acting insulin, so it takes a few days for a change of dose to be effective. If switching basal doses for weekends then Tresiba wouldn’t be the right insulin in my view (I’m just a T1, not a dsn or consultant).
I ended up being referred for a pump, and Omnipod is great for me. I don’t have any reaction to the sticky pad or the cannula, and can tweak for DP and reduce basal for activity. For someone with unpredictable or varying days, I would advocate trying Omnipod.
 
etmsreec said:
For someone with unpredictable or varying days, I would advocate trying Omnipod.
Click to expand...
Why specifically the OmniPod?
Surely, any pump allows daily (hourly) basal changes
Bearing in mind some NHS diabetes clinics consider Omnipod too expensive, focusing on one pump is too restrictive.
I understand the OP had previous problems with Medtronic but there are other pump options.
In fact, as they had issues with the cannula, a patch pump may be too limiting.
 
Tresiba is extremely flexible when it comes to the timing of doses. The mode of action which means it can do that also means it’s not very flexible/reactive to changes in the amount injected.
It reaches a steady state which allows it to give very flat release profile but changes take days to have an impact.
All explained here for the techies interested

 
Hey. Had the same issue, but it's best to notice WHEN the hypo's occur. My long story very short, you have to play around with lower dosis' and of course very similar controlled meals. There's a 2-odd-day delay for it to kick in, so what will happen is a layer on layer of long effect insulin that will continue the hypos. It depends on the layers of the old insulin...

I was on a mix insulin and then I injected two different pens and had to play around a long time. The only thing I found out is that tresiba kinda runs out. As if I leave it, let's say 6 hours and I forgot to inject... I would notice it.

So, if you're injecting morning or before bed, you may want to change them over. It worked for me and with great results. I found that my metabolism slows down in the evening so typically I have to do fast and slow in various proportions until a fix sticked!

My big change was in the night and a slight reduction from 47 to 41 by small multiples of 1 or 2 to get the sweet mark.. ended up with around 86% control throughout the day with few hypos. Took about 6 months.... so it's not easy.
 
Hi Victry77, I read recently one of the quotes from Dr Bernstein in which he says that he prescribes Metformin for T1Ds whose bsl control fluctuates with monthly cycles or adolescent growth spurts. No dosing regime mentioned but maybe your could ask your doctor and DSN about that strategy rather than trying to anticipate with a long-long acting insulin. Best Wishes.
 
searley said:
Your best bet in uncertain cases is not to adjust the tresiba as all changes can take 48 to 72 hrs to take effect.. you best bet would be micro doses of you fast acting to control your levels
Click to expand...
hi there i am richard white with type 1 diabetes and i am on tresiba and i most time stable with my night sugars but i
do have speak to my nurse at the southmead hospil to get more dose or have less dose
 
I wonder how you’ve settled down with the Tresiba now?? I am the same as you and struggle with hormone fluctuations (with little to no predictable pattern) and my diabetic nurse put me on Tresiba but I decided to not take it because it seemed entirely inappropriate for my needs.

I stuck with Levemir and fluctuate so much that my needs go from 3 units at night (still can hypo) to 6 units at night (still experience dawn phenomenon). I also find I will hypo LOADS for a couple days before my hormones change and my ratios go from 1:12 to 1:5 (which is scary as hell the other way round) It seems like nothing is actually a gift to diabetes, it’s all hard work and trial and error. Diabetic nurses don’t often know what is best for us either.
 
Back
Top