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Newly diagnosed T1 - efficacy of GAD test?
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<blockquote data-quote="Daibell" data-source="post: 1062133" data-attributes="member: 21149"><p>I'm afraid your consultant is wrong. T1 can be caused by things other than GAD antibodies such as pancreatitis, viruses and so on. There are also rarer anti-bodies which aren't always included in the GAD test. Even NICE in the UK says in their latest Diabetes Guidelines that GAD tests become less reliable as the diabetes progresses, whereas c-peptide becomes more reliable. I had a GAD done 8 years after a default initial diagnosis with 'T2' and it came back as negative. In my case I suspect a virus or mild pancreatitis as a blood test taken around diagnosis time showed a high unexplained white cell count and I had mild abdominal pain. I don't think GAD tests are affected by taking insulin.</p></blockquote><p></p>
[QUOTE="Daibell, post: 1062133, member: 21149"] I'm afraid your consultant is wrong. T1 can be caused by things other than GAD antibodies such as pancreatitis, viruses and so on. There are also rarer anti-bodies which aren't always included in the GAD test. Even NICE in the UK says in their latest Diabetes Guidelines that GAD tests become less reliable as the diabetes progresses, whereas c-peptide becomes more reliable. I had a GAD done 8 years after a default initial diagnosis with 'T2' and it came back as negative. In my case I suspect a virus or mild pancreatitis as a blood test taken around diagnosis time showed a high unexplained white cell count and I had mild abdominal pain. I don't think GAD tests are affected by taking insulin. [/QUOTE]
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