http://www.novonordisk.com/press/se...ba5-a629-415015dfa785&sShowLanguageCode=en-GB
In this 2-year (1 year initial and 1 year extension) phase 3a study, comparing the efficacy and safety of once-daily insulin degludec versus once-daily insulin glargine (both in combination with OADs), the rates of overall hypoglycaemia were similar between the two groups (1.72 [insulin degludec] versus 2.05 [insulin glargine] episodes per patient per year, p=NS). Furthermore, while the rates of severe hypoglycaemia were infrequent, they were significantly lower with insulin degludec compared with insulin glargine (0.01 [insulin degludec] versus 0.02 [insulin glargine] episodes per patient per year, p=0.02). This randomised, open-label, treat-to-target study included 1,030 patients with type 2 diabetes not previously treated with insulin, of which 659 completed 2 years of treatment1.
In this 2-year (1 year initial and 1 year extension) phase 3a study, comparing the efficacy and safety of once-daily insulin degludec versus once-daily insulin glargine (both in combination with OADs), the rates of overall hypoglycaemia were similar between the two groups (1.72 [insulin degludec] versus 2.05 [insulin glargine] episodes per patient per year, p=NS). Furthermore, while the rates of severe hypoglycaemia were infrequent, they were significantly lower with insulin degludec compared with insulin glargine (0.01 [insulin degludec] versus 0.02 [insulin glargine] episodes per patient per year, p=0.02). This randomised, open-label, treat-to-target study included 1,030 patients with type 2 diabetes not previously treated with insulin, of which 659 completed 2 years of treatment1.
