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Normalised OGTT - diabetes in remission

CherryAA

Well-Known Member
Messages
2,170
Type of diabetes
Type 2
Treatment type
Diet only
A study came out recently : http://drc.bmj.com/content/4/1/e000258

which claims to have put pre-diabetes into " remission" as follows:

"We recruited and randomized 24 pre-diabetes women and men to either a HP (30% protein, 30% fat, 40% carbohydrate; n=12) or HC (15% protein, 30% fat, 55% carbohydrate; n=12) diet feeding study for 6 months in this randomized controlled trial."

The study claims that switching carbs for proteins will put pre-diabetics into remission for 100% of the prediabetic sample.

Their definition is that an OGTT returns to normal within 2 hours of ingestion.

That is no doubt true. However the PRIME reason it will do is is probably that it decreased the carbohydrates in the diet . The human body is very sensitive to too much carbohydrate and thus anything that reduces them as proportion (or fixed amount) of the overall diet from the current way too high levels will improve matters.

This 6 month study showed an improvement from 42 to 36 in hba1C over 6 months in 24 pre-diabetic patients using a 30% protein, 40% carb and 30% fat ratio .

Very many of you will have seen SIGNIFICANTLY BETTER IMPROVEMENTS within 6 months with SIGNIFICANTLY HIGHER HBA1C LEVELS AT DIAGNOSIS also improving to NON DIABETIC SCORES

As many of you will know each of @bulkbiker, @ bluetit and myself did OGTT tolerance tests in the last month .( I do not have full info for @bluetit, so I have not included that data in the attached graphic . Overall she reported a slightly slower response then the other two, but still down to a normal Kraft pattern response within 3 hours. )

@bulkbiker and I both started with severe diabetes, Hba1C of 90 and 87 respectively. Both of us have seen dramatic improvements . At the one year stage I am now at Hba1C of 42, @bulkbiker is at Hba1C of 29 at the end of year 2. Both of us followed an LCHF diet for the first year. @bulkbiker now defines his diet as ketogenic being very low carbs ( under 20g) for the second year). I am also in ketosis at low levels but I define my diet as being LCHF as I am still eating upto about 40g carbs on many days.

The results of our Oral Glucose Tolerance Tests came out pretty much exactly the same as each other .

BOTH OF US ALSO PASS THE CRITERIA OF NORMAL HBA1C AT TWO HOURS

A non diabetic young friend of mine aged 27 also did the OGTT today. She is wearing a libre, so that we can see how our foods ( which are often the same impact both of us) . She has a BMI of 27.6, A recent LCHF convert and looking at the Kraft curves is starting to move down the path towards metabolic ill -health ( as will be 100% of the population eating a processed food/ seed oil diet) .

I thought people might be interested to see the results of all three of us compared to the Kraft definition of "Normal" and Hyperinsulinaemia and the study outlined above which is one of the few to actually provide OGTT data.


Elsewhere I have posted at length my belief that High Circulating Insulin is the disease and everything else including diabetes simply a manifestation of it instead of the current wisdom that being overweight causes diabetes and being diabetic causes disease. Instead I believe that having High Circulating Insulin is itself the disease. The disease is caused by the ingestion of too many carbohydrates in the diet coupled with industrial seed oils. The test for knowing if you have High Circulating Insulin -s fasting insulin a standard blood test.

So how did we do for under that measure as well.?

You will see from this data that @bulkbiker has managed to get his fasting insulin down to the healthy range ( 2-6) after two years effort. Mine is still coming down. it was 20 after 6 months on LCHF, 8.3 after 12 months . I need it to get down to 5 to get out of the danger zone for other disease including diabetes. Getting fasting insulin down appears to be time related depending on how severe your starting point.

It is important to appreciate that for ALL of us,our actual glucose responses on a 24/7 basis are below the green line because none of us actually ingest carbs to any great extent other than when doing an OGTT. Those following high carbs will often be ingesting carbs at this level every day and some multiple times per day. Thus we are currently at the very low ( and healthy) end of the fasting insulin range which is now stated to be normal 2-25 iuI /ml (12- 150 p/mmol range )
 

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