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Message: <blockquote data-quote="LittleGreyCat" data-source="post: 2323074" data-attributes="member: 6467">[USER=532290]@exmoortom[/USER] I would regard this as a wake up call.One view on progression to full blown T2 diabetes is:<ol> <li data-xf-list-type="ol">You body (possibly due to eating too many carbohydrates) begins to develop Insulin Resistance (IR). Your body reacts to the IR by producing more insulin to keep your BG normal. At this point it is probable that only a test for insulin production can show that anything is going on. [The NHS doesn't test for this.] A side effect over over producing insulin is that you store more fat and become more hungry for carbohydrates. Which in turn increase IR and drives up insulin production. This is sometimes referred to as Metabolic Syndrome. It also supports the view that you don't cause diabetes by getting fat, but the Metabolic Syndrome (which is a precursor to diabetes) drives a vicious circle which makes you fat. So becoming fat is a symptom not a cause.</li> <li data-xf-list-type="ol"> After a time (years, even decades) your pancreas can't keep up with the ever growing demand to produce more insulin to overcome the ever increasing IR. At that point your BG starts to creep above normal (pre-diabetes), and generally gets progressively worse if you don't take action and change something.</li> <li data-xf-list-type="ol">After some more time your pancreas is struggling more and more and your BG gets high enough for you to be diagnosed with full blown T2.</li> <li data-xf-list-type="ol">Sometimes, after this extended period of abuse your pancreas starts to flame out and the amount of insulin it can produce decreases. The IR doesn't decrease though unless fairly drastic action is taken.</li> <li data-xf-list-type="ol">The smoking, guttering ruins of you pancreas gives up entirely and to survive you have to inject insulin.</li> </ol>Under this view, if you can take action before Stage 4, then you can reduce IR, reduce the load on your pancreas, and return to "normal" BG control, which could be viewed as remission or cure.Note however that you have only dropped back to Stage 1 where your pancreas can manager to overwhelm the IR. Unless the IR is vastly deduced it is relatively easy to tip the balance the other way and get back into Stage 2.If you follow this view, then having demonstrated that you can overwhelm your pancreas then you should aim to treat your pancreas as gently as possible, by not eating things (carbohydrates) which make it work hard, and also by losing fat stores which contribute to IR.I wouldn't really consider anyone cured - just my personal prejudice - because once you have demonstrated that you can overwhelm your pancreas then you know that you can do it again if you follow the same lifestyle.Noting the oft quoted 80:20 rule that 80% of overweight/obese people do not develop T2 diabetes.So presumably either they don't develop IR or they have a rough, tough pancreas that can handle anything.<img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite6" alt=":cool:" title="Cool    :cool:" loading="lazy" data-shortname=":cool:" /></blockquote>

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