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Prof Roy Taylor hypothesis - DIRECT study & pancreatic fat
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<blockquote data-quote="AdamJames" data-source="post: 1642361" data-attributes="member: 459333"><p>Yes, I gather that there are a great many reasons why an HbA1c result may not be the best indicator.</p><p></p><p>What I find frustrating is that even the OGTT has limitations and the results can be influenced in unclear ways.</p><p></p><p>It's known that it's best to have a normal carb intake in the day or two leading up to an NHS-style OGTT, so that your body is "ready to process carbs".</p><p></p><p>I've also found, in my experiments which I try to do as consistenly as possible, that there are factors which have an effect which I haven't worked out yet.</p><p></p><p>For example I do a 34 gram carbohydrate tolerance test in a very controlled way. I did one before I started to lose weight. After 3 stone lost, I repeated it and got a result which was just within non-diabetic range, so wondered if I'd gone into remission. But a few days later I repeated it again, and it was worse than the first one!</p><p></p><p>Some things I am trying: 1) What's the effect of eating a consistent amount of carbs in the days before the test, 2) What's the effect of eating a lot of fat the days before the test, and 3) What's the effect of doing more / less exercise the days before the test.</p><p></p><p>I'm pleased to say that I managed to get non-diabetic results again, after eating very little fat and doing plenty of exercise in the run up to the test. But I still haven't worked out the important factors. And I am in no doubt that in spite of it being possible to get this great result, I'm currently *managing* diabetes, I'm not in remission!</p></blockquote><p></p>
[QUOTE="AdamJames, post: 1642361, member: 459333"] Yes, I gather that there are a great many reasons why an HbA1c result may not be the best indicator. What I find frustrating is that even the OGTT has limitations and the results can be influenced in unclear ways. It's known that it's best to have a normal carb intake in the day or two leading up to an NHS-style OGTT, so that your body is "ready to process carbs". I've also found, in my experiments which I try to do as consistenly as possible, that there are factors which have an effect which I haven't worked out yet. For example I do a 34 gram carbohydrate tolerance test in a very controlled way. I did one before I started to lose weight. After 3 stone lost, I repeated it and got a result which was just within non-diabetic range, so wondered if I'd gone into remission. But a few days later I repeated it again, and it was worse than the first one! Some things I am trying: 1) What's the effect of eating a consistent amount of carbs in the days before the test, 2) What's the effect of eating a lot of fat the days before the test, and 3) What's the effect of doing more / less exercise the days before the test. I'm pleased to say that I managed to get non-diabetic results again, after eating very little fat and doing plenty of exercise in the run up to the test. But I still haven't worked out the important factors. And I am in no doubt that in spite of it being possible to get this great result, I'm currently *managing* diabetes, I'm not in remission! [/QUOTE]
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