Hello, I thought I would give you my experience on Dapagliflozin (Forxiga), I was first in my medical practice to try it when I was in Scotland UK and I started it in October 2013. The doctors had just had the sales rep in the surgery and i was keen to be the guinea pig. I was already taking 2000 Metformin and additional Sitagliptin made no difference in controlling my blood sugar, so that's why I was prescribed it. Apologies to any men reading the next bit - I think one of the following side effects may affect females only.
I noticed an immediate increased urination every day about 2-3 hours after taking my morning tablet and extra thirsty. By the end of the first week I had raging thrush and was very miserable. However the doc prescribed me Canesten pessaries (rather than the tablet form which will kill good bacteria in your gut as well as in your ladygarden!) to be taken when required and I decided to work through it as I had already lost half a stone!!! After a few weeks I got into the good habit of taking the Canesten once per week as a preventative measure. The one week I forgot, the thrush was back so I hope that tip helps others. But every 3 months at the chemist, I had a fight to pick up my 12 Canesten pessaries, they are so interfering they question why you would get thrush so much and think the doctor has made a mistake on the prescription.
Today, 8 months later I got my best ever blood results back HBA1C= 6.4. and my new GP (in Australia) has suggested that I now stop the Forxiga as I have lost... wait for it.... 30KG (4 stones & 10lb) in the 8 months I have been on it. I am delighted as Forxiga is only available to me in Australia on a private prescription over $300 per month which is beyond my means. (God bless the NHS in Scotland)
As for other side effects I don't remember any to be honest. I have multiple health conditions and take all sorts of medication but this is the best I have felt for years (age 50). I do get mild hypos but just carry glucose tablets and have a banana. The side effects of starting Metformin were much worse than Forxiga, although they improved after a few weeks.
I hope this helps anyone thinking of giving it a try. It has made me lose a huge amount of weight which was a major issue in my life. My advice would be think positively and be determined to work through any side effects and use the Canesten preventatively.
Best wishes, Lucie