Hello Pink Orchid,
I've had Polymyalgia for about 10 years. This is unusual, as it usually goes into remission before that. I have taken Prednisolone for all that time, in various doses depending on flare ups, and 2 bouts of Giant cell Arteritis/Temporal Arteritis - (very nasty, and the only treatment is high doses, 70 mg, of prednisolone. It is something that polymyalgia sufferers have to watch out for, although there are some cases of it developing without the polymyalgia as a precursor). One consultant tried to switch me to methotrexate as a steroid sparer. It works for some people with PMR, but you have to have blood tests every 2 weeks, and then every month. These showed that my liver was reacting badly, so I was taken off them. The consultant then tried leflunomide, and I also reacted badly to that. So I gave up on the alternatives, and stuck with the prednisolone.
The diabetes started about 2 years ago, and was diagnosed with steroid induced diabetes. I had already started losing weight very slowly using Hairy Bikers Cook Books, but then I was diagnosed with Rheumatoid Arthritis. A different consultant decided to have another try with methotrexate, as by this time I had lost 11 stone (thank you LCHF) and she thought that might mean a different reaction from my liver. It did, and I've managed to decrease my Prednisolone dose as my methotrexate has increased. Good thing really, as the surgeon who is planning my knee replacement in the new year won't do it until my Prednisolone is down to 5 mg. I've just reached that.
About 4 years ago I had a bout of hip bursitis, which resulted in being hospitalised for a few days until I could move again. The hospital added amylotryptilin as Daibell mentions above. It helped with the hip pain, (totally different to PMR pain) but had no effect on the polymyalgia, and I've never come across anyone else with polymyalgia who has used it successfully. Polymyalgia is well known for being resistant to pain killers, and most anti-inflammatories. Indeed one of the diagnostic indicators of polymyalgia is that it doesn't respond to pain killers, but Prednisolone will have a effect within a few days.
So, there are one or two alternatives to Prednisolone for polymyalgia, but the medics don't usually try those unless you are having difficulties getting your steroid dose down. And they work for some people and not for others).
I've never been on insulin, so I was interesting to read Sid's comments, in case my polymyalgia flares again.
Margaret