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Message: <blockquote data-quote="Chris24Main" data-source="post: 2743022" data-attributes="member: 585131">[USER=569488]@Bcgirl[/USER] and [USER=520626]@Melgar[/USER] - I have a feeling that the two of you can really learn something from each other. Other than the acute β-cell failure that must have been present for me for a while, and then then question of whether a period of insulin gave my pancreas a rest to allow recovery, there is no evidence that my pancreas is anything other than normal now.However - if I can just dip my toe into what may be unwanted territory - there are those (Ben Bikman obviously coming to mind, but not at all the only example) - who say that Hashimoto's is a direct result of insulin resistance. More than that, in this thread, over and over, I've simplified insulin resistance by describing is as a natural reaction to too much of a thing.. but when you talk about it like a cellular biologist, elevated insulin is only one of the major causes - the others being stress hormones and inflammation.anything that ends with -itis is inflammation.So then, you get into a positive feedback loop - inflammation can cause insulin resistance, and insulin resistance can cause inflammation.Kind of like saying "a spark can cause fire, and fire can cause sparks" On the one hand, that doesn't help - it's just an annoying and banal truism - on the other, understanding the relationship between sparks and fire; it's beyond common sense that you would not worry about defining what a spark is, you would look to put the fire out.And that's kind of where I am right now - the more complicated things get - the more connections you can see, but the more that the simple concepts just help everything - even a completely healthy body is constantly in a battle between things that inflame cells (toxins, infections etc), or cause them to produce energy in a non-optimal way (oxidative stress) that cause the same inflammation from the byproducts (think of smoke from a fire not burning properly) like ROS - that we may recognise as free radicals.Our systems for dealing with all of that are even more complex, but for many of us, they are ether overwhelmed dealing with the effects of high blood glucose, or toxins from all sorts of modern changes to the living environment, or just plain go rogue, leading to the auto-immune conditions.Make it as easy as possible for your anti-inflammatory crew.</blockquote>

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