Trinkwasser
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Assimilator1 said:Trinkwasser said:Interesting stuff, I haven't (yet) had this one but have been prone to many minor but annoying things to do with connective tissue.
Long term keeping BG tightly controlled is probably the best plan, it's the glycation of the tissues which seem to be behind these issues. And yes, they can occur while you are at "not diabetic yet" BG numbers.
Care to expand on that? I have multiple problems with various joints & muscles, stiffness, aching, straining & joints clicking a lot. I don't know if there's any connection to my Type1 but I'll take in any info
Sorry my collection of websites and downloaded papers is undergoing maintenance at the moment but over time I've seen many threads like this concerning carpal tunnel, tenosynovitis, frozen shoulder and similar conditions, also various forms of arthritis, gout, pseudogout etc.
Common factors to many of these and other diabetic complications is the various damage mechanisms including but not limited to Advanced Glycation Endproducts (AGE, aptly enough), inflammatory cytokines (including those put out by body fat, principally in Type 2s), oxidative stress, and again principally in Type 2s hyperinsulinemia required to overcome insulin resistance, all alongside the direct and sometimes acute problems from BG spikes.
Then the factors interract, nerve damage worsens circulation, poor circulation worsens nerve damage etc, probably a good starting point would be
http://www.nlm.nih.gov/medlineplus/diab ... tions.html