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Message: <blockquote data-quote="Spiker" data-source="post: 931574" data-attributes="member: 102150">This is the article that demonstrates 2/daily Lantus is more effective than 1/daily Lantus<a href="http://www.ncbi.nlm.nih.gov/pubmed/16911626" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/16911626</a>Diabet Med. 2006 Aug;23(8):879-86.Twice-daily compared with once-daily insulin glargine in people with Type 1 diabetes using meal-time insulin aspart.Ashwell SG1, Gebbie J, Home PD.CONCLUSIONS:Blood glucose concentration rises in the late afternoon in association with falling plasma insulin levels towards the end of the 24-h period after insulin glargine injection in some people with Type 1 diabetes using once-daily glargine at dinner-time plus a rapid-acting insulin analogue at meal-times. This is prevented by twice-daily injection of insulin glargine.</blockquote>

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