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<blockquote data-quote="Dennis" data-source="post: 60113" data-attributes="member: 1338"><p>Hi Patch,</p><p></p><p>Someone who has a very high degree of insulin resistance needs to take high doses of metformin or one of the glitazone meds and also needs to exercise and lose weight. There is a limit to how much meds can be taken, and the exercise and weight loss route takes quite a long time to reduce resistance. Also there is a limit to how much insulin a pancreas can produce. So in a situation where a patient is on maximum meds and just can't produce any more insulin, and has increasing BS, then the only recourse is to injected insulin until the insulin resistance can be reduced enough so that the body's own insulin is able to cope.</p></blockquote><p></p>
[QUOTE="Dennis, post: 60113, member: 1338"] Hi Patch, Someone who has a very high degree of insulin resistance needs to take high doses of metformin or one of the glitazone meds and also needs to exercise and lose weight. There is a limit to how much meds can be taken, and the exercise and weight loss route takes quite a long time to reduce resistance. Also there is a limit to how much insulin a pancreas can produce. So in a situation where a patient is on maximum meds and just can't produce any more insulin, and has increasing BS, then the only recourse is to injected insulin until the insulin resistance can be reduced enough so that the body's own insulin is able to cope. [/QUOTE]
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