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Type 2 now no longer producing insulin
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<blockquote data-quote="LittleGreyCat" data-source="post: 2179674" data-attributes="member: 6467"><p>LADA is, I think, typically an autoimmune disease which destroys the Beta cells (as in full on T1) but just takes a while to do it, so initially presents as T2 whilst some insulin is being produced but gradually goes to T1 when all significant insulin production ceases.</p><p></p><p>There is often a honeymoon period for T1s when the Beta cells are still fighting back, but I think this is usually no more than a year. LADA has an extended honeymoon period, and although there is a lot of debate I don't think it often extends beyond 6 years. Your period of about 35 years between first diagnosis and the final ending of insulin production does not sound like LADA.</p><p></p><p>Your very high insulin resistance could indicate that your pancreas has just worn out from over use.</p><p></p><p>As you say, you could have developed T1 independently of your existing T2; that is, had an autoimmune response which destroyed your Beta cells. That would be interesting, to say the least, but that doesn't really help you now. I haven't seen anyone on this forum who has gone the same route, but I may well have missed them.</p><p></p><p>I assume that once a diagnosed T2 has ceased insulin production then your treatment regime would be the same as for a T1 with perhaps something additional because of your very high insulin resistance. Presumably as a T2 you were also being treated for the insulin resistance so I can't see any major change there. Potentially more insulin required than would be expected for a newly diagnosed T1.</p><p></p><p>Do you have any indication why you have very high IR?</p><p>Is your weight average?</p><p>What do you eat?</p><p>Has your health team made any suggestions about the cause?</p></blockquote><p></p>
[QUOTE="LittleGreyCat, post: 2179674, member: 6467"] LADA is, I think, typically an autoimmune disease which destroys the Beta cells (as in full on T1) but just takes a while to do it, so initially presents as T2 whilst some insulin is being produced but gradually goes to T1 when all significant insulin production ceases. There is often a honeymoon period for T1s when the Beta cells are still fighting back, but I think this is usually no more than a year. LADA has an extended honeymoon period, and although there is a lot of debate I don't think it often extends beyond 6 years. Your period of about 35 years between first diagnosis and the final ending of insulin production does not sound like LADA. Your very high insulin resistance could indicate that your pancreas has just worn out from over use. As you say, you could have developed T1 independently of your existing T2; that is, had an autoimmune response which destroyed your Beta cells. That would be interesting, to say the least, but that doesn't really help you now. I haven't seen anyone on this forum who has gone the same route, but I may well have missed them. I assume that once a diagnosed T2 has ceased insulin production then your treatment regime would be the same as for a T1 with perhaps something additional because of your very high insulin resistance. Presumably as a T2 you were also being treated for the insulin resistance so I can't see any major change there. Potentially more insulin required than would be expected for a newly diagnosed T1. Do you have any indication why you have very high IR? Is your weight average? What do you eat? Has your health team made any suggestions about the cause? [/QUOTE]
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