Type 2 Types of type 2 diabetes

[saky]

Sub types of diabetes like MOD(mild obesity related diabetes), MARD(mild age related diabetes), SIDD(severely insulin deficient diabetes) SIRD (severe insulin resistant diabetes) CIRD(combines insulin resistant and deficient diabetes)
Can you throw more light on that?

 

[HSSS]

I believe these are sub types proposed by researchers a few years back that don’t seem to have been adopted. Fundamentally it’s suggesting there are different triggers for type 2 and it’s not one homogenous disease. Having read many different experiences in here and else where over the last 4 or 5 years it certain seems true that we do have different triggers and different results from the same regimes so personally I’d like to see this delved into further as I think there’s a lot to it. Eg some respond extremely well (bgl wise) to simple weight loss, others either have none to lose or it makes little difference. Some can tolerate a lot more carbs than others, some regain some insulin sensitivity others less so. And the differences are not just on how long you’ve been diagnosed either. I strongly suspect different causes and subtypes

 

[Lamont D]

Sub types of diabetes like MOD(mild obesity related diabetes), MARD(mild age related diabetes), SIDD(severely insulin deficient diabetes) SIRD (severe insulin resistant diabetes) CIRD(combines insulin resistant and deficient diabetes)
Can you throw more light on that?

Hi, I could just say, that is a description of how doctors assess patients with a diagnosis in mind.
You have missed out others such as brittle diabetes, hyperinsulinimia, hyperglycaemia, hypoglycaemia in many forms, and many, many others.
I have often thought that because we measure diabetes through an hba1c test, We are missing something more important, such as insulin levels. One of the main reasons for insulin resistance and hyperglycaemia is high circulating insulin levels. Which is not used.

I think the most important thing is treatment.
Instead of doctors, not understanding how critical, dietary management is, to patients and get the individuals proper treatments, wether dietary or meds, exercise. We are all different and so should the treatment. One size doesn't fit all.

Understanding the differences in those descriptive diagnosis should be explained to patients.
That is if, the majority of GP's, just don't get the training or understand the logistics or the fundamentals of how we get diabetes.
For example, an annual MOT test. Which includes a full blood panel, with hba1c and insulin levels. Would be a step in the right direction. Prevention.

Great question, it might not be the answer you want, but we are only lay people who have gone through the big questions! How and why? Then the What to do?
Best wishes.

 

[Diablo T2]

Sub types of diabetes like MOD(mild obesity related diabetes), MARD(mild age related diabetes), SIDD(severely insulin deficient diabetes) SIRD (severe insulin resistant diabetes) CIRD(combines insulin resistant and deficient diabetes)
Can you throw more light on that?

I can't throw more light on that but it is a good question to ask. I have not seen these sub-type definitions before but I have been wondering about my own status, i.e. am I SIDD, SIRD or CIRD (I tried to articulate this in my own words up until now). I've managed to get to normal HbA1c levels so only now have an annual HbA1c and diabetic eye screening which is unlikely to give any further to insight as to which sub-type I may be. I've been considering having a private test for insulin levels/insulin resistance as that may give a clue. Key to me is if I am more toward SIDD it is unlikely to change, whereas if I am more toward SIRD there may be a possibility for further improvement.

I do agree with @Lamont D that an annual MOT inclusive of insulin levels would make sense - surely there'd be a strong economic case for emphasis on prevention.

 

[Outlier]

I do agree with @Lamont D that an annual MOT inclusive of insulin levels would make sense - surely there'd be a strong economic case for emphasis on prevention.

That's sensible and logical, but it "costs" more on some of the balance sheets and doesn't make money for Big Pharma.

 

[AndBreathe]

Sub types of diabetes like MOD(mild obesity related diabetes), MARD(mild age related diabetes), SIDD(severely insulin deficient diabetes) SIRD (severe insulin resistant diabetes) CIRD(combines insulin resistant and deficient diabetes)
Can you throw more light on that?

I think these sub-types or more likely, refined titles were coined after a piece of research https://pubmed.ncbi.nlm.nih.gov/35607770/

I think it would certainly be useful to understand which sort of T2 each of us might be, but asking a GP for the supporting tests, and getting them, is another matter. X person might say they were very overweight at diagnosis, therefore they have to be MOD, but in this life and certainly with diabetes, assumptions make asses of us something.

 

[saky]

I can't throw more light on that but it is a good question to ask. I have not seen these sub-type definitions before but I have been wondering about my own status, i.e. am I SIDD, SIRD or CIRD (I tried to articulate this in my own words up until now). I've managed to get to normal HbA1c levels so only now have an annual HbA1c and diabetic eye screening which is unlikely to give any further to insight as to which sub-type I may be. I've been considering having a private test for insulin levels/insulin resistance as that may give a clue. Key to me is if I am more toward SIDD it is unlikely to change, whereas if I am more toward SIRD there may be a possibility for further improvement.

I do agree with @Lamont D that an annual MOT inclusive of insulin levels would make sense - surely there'd be a strong economic case for emphasis on prevention.

CIRD is combined insulin resistance and insulin deficient form of diabetes.. common in Indian sub continent.

 

[AndBreathe]

CIRD is combined insulin resistance and insulin deficient form of diabetes.. common in Indian sub continent.

Is insulin production routinely tested on the Indian Subcontinent?

For me, personally, unless tests are done, those, and any classification is done on likelihood. In my world, likelihood is a long way from certainty.

 

[saky]

Insulin isn't routinely tested but I got mine tested in a private lab. C peptide 2ng/ml(.8-4ng/ml) and fasting insulin 6munits/L (2- 25units)
Don't why my hba1c is coming elevated again. Am doing everything right. Eating low carbs, exercising post meal etc.
Testing in another lab now.