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Type 2 Diabetes
Wake up my lazy 'B Cells'
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<blockquote data-quote="Oldvatr" data-source="post: 2409521" data-attributes="member: 196898"><p>Classic chicken and egg situation. There are actually two identified types of IR that occur in mainly T2D. One is mitochondrial IR (muscles and subcutaneous fat), and adipose IR (abdomen and visceral fat). They seem to have different trigger mechanisms and not necessarily one single solution, but that is what most people seem to assume the ND diet provides.</p><p></p><p>Roy Taylor by his work has concentrated on primarily adipose IR and he ignores the mitochondrial effects. However, the general weight loss that the diet induces would probably greatly assist that second IR by removing any fat seepage into subcutaneous cells as a serendipitous gain. His work will be of great benefit to the diabetic community and advances our understanding of the condition. But it is just the beginning, a stepping stone. And it only worked for 46% of participants who were rigorously monitored and followed up. The results in a more general slice of the public may not reach even this success rate. We are also seeing a drop-off effect with time after the trial concluded, so there is a mechanism there that needs to be staunched and understood.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 2409521, member: 196898"] Classic chicken and egg situation. There are actually two identified types of IR that occur in mainly T2D. One is mitochondrial IR (muscles and subcutaneous fat), and adipose IR (abdomen and visceral fat). They seem to have different trigger mechanisms and not necessarily one single solution, but that is what most people seem to assume the ND diet provides. Roy Taylor by his work has concentrated on primarily adipose IR and he ignores the mitochondrial effects. However, the general weight loss that the diet induces would probably greatly assist that second IR by removing any fat seepage into subcutaneous cells as a serendipitous gain. His work will be of great benefit to the diabetic community and advances our understanding of the condition. But it is just the beginning, a stepping stone. And it only worked for 46% of participants who were rigorously monitored and followed up. The results in a more general slice of the public may not reach even this success rate. We are also seeing a drop-off effect with time after the trial concluded, so there is a mechanism there that needs to be staunched and understood. [/QUOTE]
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