Over the last 3 years my HbA1c has risen steadily although not hugely significantly from 5.3 to 7. I eat a LCHF diet and take 1000mg Metformin SR per day. I suggested to my GP that perhaps I could try the Newcastle diet to see if I could get the levels back down or give them a head start. She requested that I only try it for 6 weeks as I don't have a vast amount of weight to lose so I did.... I followed the programme completely drinking those wretched shakes etc.
My GP took my bloods last week and I went to see her on Friday to get the results. VERY disappointing.
Although I had lost just over a stone in weight my HbA1c had only gone down by .6 to 6.4. My GP was quite pleased as she said that all my other readings were brilliant but I expected more!
We had a lengthy chat (surprising I know for a GP) and she put forward the theory that as I already eat a low carb diet - eating around 50g per day - but drinking the shakes (slimfast) which have 26g in each, I was consuming 78g without counting the veg which is higher than my body is used to. Therefore although I lost weight the BS reduction wasn't that great.
To test this theory she asked if I wanted to do another 6 weeks, keeping the calories to 800 per day, but not drinking any shakes, just using homemade soups instead! She is willing to repeat the tests again at the beginning of May. I am happy to do this but the only issue I have is that I can only lose about another stone or I will be underweight.
Has anyone else had this problem? If the levels don't go down (and stay down) obviously I have the option of taking more Metformin but I would like to avoid that if possible as I reduced the Metformin 2 years ago and have enjoyed not having to run to the loo every few minutes!
The first thing that sprung to my mind is the fact that a fairly large percentage (can't remember offhand) are misdiagnosed with type2 when in fact they have other forms of diabetes involving damage to the pancreas that will not react in the same way to weight loss. Another thing that I read was that even people of normal / low BMI (esp of Asian hereditary) can still have up to 20kg of visceral fat that would be unseen, unfortunately that would be difficult to diagnose. Some talk of some of that here:
http://www.ncl.ac.uk/magres/research/diabetes/documents/Diabetes-Reversaloftype2study.pdf
Also, further to earlier posts, increases in insulin resistance over time/age are entirely correlated with increase in fat/mass. e.g When a 60 year old is compared to a 20 year old with the same amount of muscle and fat they are seen to have identical insulin resistance. The "inevitable worsening" of type 2 is caused by "inevitable" increases in fat mass. Of course this is not inevitable but admittedly highly likely for most.
This newly published study may also be of interest as it "proves" rapid weight loss from a vlcd is in fact correlated with better outcomes than compared to slower weight loss."Myth number 3: Large, rapid weight loss is associated with poorer long-term weight-loss outcomes, as compared with slow, gradual weight loss."
http://www.nejm.org/doi/full/10.1056/NEJMsa1208051#t=articleBackground
"Within weight-loss trials, more rapid and greater initial weight loss has been associated with lower body weight at the end of long-term follow-up.
9,10 A meta-analysis of randomized, controlled trials that compared rapid weight loss (achieved with very-low-energy diets) with slower weight loss (achieved with low-energy diets — i.e., 800 to 1200 kcal per day) at the end of short-term follow-up (<1 yr) and long-term follow-up (≥1 year) showed that, despite the association of very-low-energy diets with significantly greater weight loss at the end of short-term follow-up (16.1% of body weight lost, vs. 9.7% with low-energy diets), there was no significant difference between the very-low-energy diets and low-energy diets with respect to weight loss at the end of long-term follow-up.
10Although it is not clear why some obese persons have a greater initial weight loss than others do, a recommendation to lose weight more slowly might interfere with the ultimate success of weight-loss efforts.