But the 10 minute at 15mmols won't be a true reflection, you'd need to measure it over the hour to see the rise and fall as you'll get an arc in the readings. Sometimes the rise and decline to 15mmols can be over a sustained period . So to effect, you're average comparable is wrong. Need to compare like for like, in this case, you'd need to adjust 8mmol for 10 minutes.Hi Westley,
I work in pharma, where we need to calculate the exposure someone has had to something (e.g. a drug). What does the damage in diabetics is exposure to glucose. We calculate exposure by looking at a line graph of time on the x-axis and concentration on the y-axis. The exposure is calcualted by the area that is under the line.
We can easily calculate the exposure to glucose in the examples you gave:
Exposure = time x concentration
For 60 mins at 8 mmols/l:
60 x 8 = 480
For 10 mins at 15 mmols/l:
10 x 15 = 150
So, you're more exposed to glucose when you spend an hour at 8 mmol/l. However, there are three points to make: is 8 a safe level? Will you only ever be 10 mins at 15? What is an unsafe exposure?
If we consider that 'normal' people do not suffer diabetes complication damage, then we should only consider the period where bgl exceeds the upper limit for a normal non-diabetic.But the 10 minute at 15mmols won't be a true reflection, you'd need to measure it over the hour to see the rise and fall as you'll get an arc in the readings. Sometimes the rise and decline to 15mmols can be over a sustained period . So to effect, you're average comparable is wrong. Need to compare like for like, in this case, you'd need to adjust 8mmol for 10 minutes.
If we consider that 'normal' people do not suffer diabetes complication damage, then we should only consider the period where bgl exceeds the upper limit for a normal non-diabetic.
In this context, 8 is not high in comparison to 15, and it would really depend over an extended period where you were sitting. To put the eight into context, an Hba1C of 7.5% is roughly the equivalent of an average of 7.7 mmol/l.
My bad. In which case it is 6.5% that is 7.7mmol/l and I am confusing the two.
Also to respond to @tim2000s point about the damaging effect of rapid changes, I suppose a better measure should also factor this in somehow.
Basically, that's what it seems to suggest.It's an interesting point about the rapid change. I wander if you had very high bg level it would be better to bring it down slowly.
In years gone by if I had a unexpected high reading I'd try and bring it down doubly as quick by over correcting then eating 90 mins later. This could possibly be more harmful.
If we consider that 'normal' people do not suffer diabetes complication damage, then we should only consider the period where bgl exceeds the upper limit for a normal non-diabetic.
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